Effects of remote ischemic preconditioning on central nervous system regeneration

Persistent ID (NDL): info:ndljp/pid/12071403

Material type: 博士論文

Author: 長谷川, 緋里

Publisher: -

Publication date: 2021-03-05

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use at the National Diet Library

本資料は、掲載誌(URI)等のリンク先にある学位授与機関のWebサイトやCiNii Dissertationsから、本文を自由に閲覧できる場合があります。

Notes on use

Note (General)：: We examinated the effect of non-lethal remote ischemic preconditioning (RIPC) on central nervous system regeneration. CB17 mice were divided into 3 tr...

Search by Bookstore

Read this material in an accessible format.

View materials in accessible formats for people with print disabilities (1Type)

Search by Bookstore

Read in Disability Resources

Other Services
- テキストデータ check it on 国立国会図書館デジタルコレクション

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Effects of remote ischemic preconditioning on central nervous system regeneration
Author/Editor: 長谷川, 緋里
Author Heading: 長谷川, 緋里
Publication Date: 2021-03-05
Publication Date (W3CDTF): 2021-03-05
Alternative Title: 遠隔虚血負荷が中枢神経再生能に及ぼす影響
Degree grantor/type: 大阪歯科大学
Date Granted: 2021-03-05
Date Granted (W3CDTF): 2021-03-05
Dissertation Number: 甲第894号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 甲第894号
Text Language Code: eng
Subject Heading: ishcemic preconditioning
RIPC
Target Audience: 一般
Note (General): We examinated the effect of non-lethal remote ischemic preconditioning (RIPC) on central nervous system regeneration. CB17 mice were divided into 3 trearment groups. The femoral artery(FA) group had temporary occlusion of the bilateral femoral arteries, the middle cerebral artery(MCA) group had temporary occlusion of left middle cerebral artery, and the carotid artery(CA) group had temporary occusion of left carotid artery. Following the trearment, the expression of neural stem cells was examined by immunohistochemistory. In the FA and CA groups, nestin-positive neural stem cells were found primally in the granular layer of the hippocampal dentate gyrus(DG), which is a known site of regeneration. Glial fibrillary acidic protein(GFAP)-positive astrocytes were also observed, and a subset of GFAP-positive cells also stained positive for nesitin. These findings suggest that RIPC induces endogenous neural stem cells in the hippocampal DG. Double staining further suggested the presence of astrocytes that are reactive to tissue damage. Thus, neural stem cells may be involved in regulating resistance to ischemia, and astroglia may be involved in regeneration of the nervous system.
2020年度
Persistent ID (NDL): info:ndljp/pid/12071403
https://dl.ndl.go.jp/pid/12071403
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2021-04-23
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000261/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp