Alternative Titleウサギによる大きさの異なる顆粒状異種他家骨による上顎洞底挙上術後の組織形態学的検討とμCTとの比較研究
Note (General)Purpose: The aim of the present experiment was to compare the data on new bone formation measured histologically and microtomographically in maxillary sinuses augmented with a xenograft with higher density and higher mineral content compared to the natural bone. The hypothesis was that histomorphometric and microCT analyses does not yield similar outcomes when a xenograft with higher density and mineral content compared to the natural bone is used.Methods: In 18 rabbits, the maxillary sinus was augmented bilaterally using deproteinized bovine bone mineral (DBBM) xenograft granules of either 0.125-1 mm or 1-2 mm of dimensions. The rabbits were euthanized after 2, 4, and 8 weeks of healing. Comparisons were performed between MicroCT and histological analyses.Results: After 2 weeks of healing, higher contents of bone were found at the histological compared to the MicroCT analyses in both sinuses, especially in the middle regions of the grafted sinus. Between 2 and 8 weeks of healing, new bone increased of about 21% at the histological analyses while, at the MicroCT, increased only about 4%. In the same period, the xenograft proportion decreased from 51.6±4.9% to 45.3±3.3% at the histological analyses while, at the MicroCT, the xenograft appeared to increase in percentages.Conclusion: Histological and microCT analyses yielded different outcomes when a xenograft with higher density and higher mineral content compared to the natural bone was used.
2019年度
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2022-02-06T04:33:19+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション