Note (General)We analyzed changes in airway patency at varying angles of head flexion and extension by evaluating changes in airway pressure and mucosal contact pressure using high-resolution manometry (HRM). Propofol (2 mg/kg) was administered to 24 adult patients to induce sleep, followed by a dose of rocuronium (0.6 mg/kg). Mechanical ventilation was performed with the use of 5% sevoflurane. Using HRM with a diameter of 8 Fr (2.64 mm), the larynx was expanded, followed by the fixation of sensor 1 at the soft palate, sensors 2 and 3 at the tongue root mucosa, and sensor 4 below the epiglottis. Measurement was conducted during mask ventilation using a volume-controlled respirator with the tidal volume set at 7 ml/kg and the ventilation frequency set at 10 times/min. The patient’s head was bent or extended at eight levels of flexion or extension. The mask pressure measurement and manometric measurement of airway pressure and mucosal contact pressure were conducted at intervals of 30 s. The highest mucosal contact pressure was recorded at the tongue root, indicating that the earliest obstruction of the airway occurred at this point among the four sites examined. During extension of greater than 5°, the mucosal contact pressure decreased, and the airway began to become patent. The airway patency was optimal during extension of greater than 20°, suggesting that ventilation was possible at these head positions. HRM was considered to be a useful method to assess changes in airway patency.
2019年度
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2022-02-06T04:33:19+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション