Effects of photosensitizers in a high-power, red light-emitting diode irradiation on human gingival epithelial cells

Persistent ID (NDL): info:ndljp/pid/12071529

Material type: 博士論文

Author: 中島, 幸市朗

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Publication date: 2019-06-26

Material Format: Digital

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Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: Antimicrobial photodynamic therapy has been used in clinics to minimize the susceptibility to bacterial resistance in patients with periodontal diseas...

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Material Type: 博士論文
Title: Effects of photosensitizers in a high-power, red light-emitting diode irradiation on human gingival epithelial cells
Author/Editor: 中島, 幸市朗
Author Heading: 中島, 幸市朗
Publication Date: 2019-06-26
Publication Date (W3CDTF): 2019-06-26
Alternative Title: 高出力赤色LED照射における光増感剤がヒト歯肉上皮細胞に及ぼす影響
Degree grantor/type: 大阪歯科大学
Date Granted: 2019-06-26
Date Granted (W3CDTF): 2019-06-26
Dissertation Number: 乙第1620号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 乙第1620号
Text Language Code: eng
Subject Heading: Antimicrobial
Photodynamic therapy
Photosensitizer
Epithelial cells
Target Audience: 一般
Note (General): Antimicrobial photodynamic therapy has been used in clinics to minimize the susceptibility to bacterial resistance in patients with periodontal disease. It has been proven to be effective in treating bacterial, fungal, and viral infections. However, it is hard to ignore the effects of photosensitizers on the body. We investigated the effects of two typical photosensitizers, and assessed the proliferation of human gingival epithelial cells (HGECs) and the production of inflammatory cytokines after treatment with a high-power, red light-emitting diode (LED) along with photosensitizers. We found that methylene blue promotes proliferation of HGECs, whereas toluidine blue does not. The production of the inflammatory cytokines from HGECs decreases after LED irradiation. Hence, this study suggests that LED irradiation in the presence of either of the photosensitizers reduces inflammation in dental tissues such as the epithelium of periodontal pockets.
2019年度
Persistent ID (NDL): info:ndljp/pid/12071529
https://dl.ndl.go.jp/pid/12071529
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2019-09-27
Format (IMT): application/pdf
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Periodical Title (URI): http://id.nii.ac.jp/1392/00000211/
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