Induction of Mesenchymal Stem Cells-like Cells Derived from Human Gingival iPS Cells into Osteoblast-like Cells

Persistent ID (NDL): info:ndljp/pid/12071576

Material type: 博士論文

Author: 中山, 雄司

Publisher: -

Publication date: 2018-03-09

Material Format: Digital

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Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: Mesenchymal stem cells (MSCs) have a limited capacity to proliferate in vitro, making it very difficult to acquire sufficient cell numbers for implant...

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Material Type: 博士論文
Title: Induction of Mesenchymal Stem Cells-like Cells Derived from Human Gingival iPS Cells into Osteoblast-like Cells
Author/Editor: 中山, 雄司
Author Heading: 中山, 雄司
Publication Date: 2018-03-09
Publication Date (W3CDTF): 2018-03-09
Alternative Title: 歯肉 iPS 細胞に由来する間葉系幹細胞様細胞からの骨芽細胞様細胞への誘導
Degree grantor/type: 大阪歯科大学
Date Granted: 2018-03-09
Date Granted (W3CDTF): 2018-03-09
Dissertation Number: 甲第819号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 甲第819号
Text Language Code: eng
Subject Heading: mesenchymal stem cells-like cells
mesenchymal stem cells
human gingival iPS cells
osteoblast-like cells
Target Audience: 一般
Note (General): Mesenchymal stem cells (MSCs) have a limited capacity to proliferate in vitro, making it very difficult to acquire sufficient cell numbers for implantation. The objective of this study was to induce MSC-like cells (MSLCs) from human gingival induced pluripotent stem cells (iPSCs) into osteoblast-like cells. We fabricated MSLCs from human gingival iPSCs under the feeder free condition. MSLCs expressing MSC-specific markers treated with osteoblast differentiation factor expressed osteoblast-specific mRNA and protein. Given the higher proliferative capacity of MSLCs, the cells may be a possible source for preparing osteoblast-like cells, applicable for bone regeneration therapy.
2017年度
Persistent ID (NDL): info:ndljp/pid/12071576
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Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
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Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2018-05-17
Format (IMT): application/pdf
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Periodical Title (URI): http://id.nii.ac.jp/1392/00000162/
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