Biocompatibility of titanium surface nanostructures following chemical processing and heat treatment

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Biocompatibility of titanium surface nanostructures following chemical processing and heat treatment

Persistent ID (NDL): info:ndljp/pid/12071582

Material type: 博士論文

Author: 藤尾, 美穂

Publisher: -

Publication date: 2017-03-09

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: The aims of the present study were to investigate alkali and heat treatment of titanium surfaces, and to evaluate the ability of such modified surface...

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Material Type: 博士論文
Title: Biocompatibility of titanium surface nanostructures following chemical processing and heat treatment
Author/Editor: 藤尾, 美穂
Author Heading: 藤尾, 美穂
Publication Date: 2017-03-09
Publication Date (W3CDTF): 2017-03-09
Alternative Title: 化学合成法と加熱処理を施したナノ構造析出純チタン金属表面の生体適合性
Degree grantor/type: 大阪歯科大学
Date Granted: 2017-03-09
Date Granted (W3CDTF): 2017-03-09
Dissertation Number: 甲第813号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 甲第813号
Text Language Code: eng
Subject Heading: implant
nanostructure
rat MSC
Target Audience: 一般
Note (General): The aims of the present study were to investigate alkali and heat treatment of titanium surfaces, and to evaluate the ability of such modified surfaces to improve osteogenic differentiation of rat bone marrow (RBM) cells to increase the success rate of titanium implants. To improve bone differentiation on titanium alloy implants, titania nanosheet (TNS) structures were fabricated on titanium surfaces by NaOH and heat treatment at 200, 400, 600, and 800°C. Cell behavior on heat- treated TNS-modified titanium was investigated, and the ability of the modified surfaces to affect osteogenic differentiation of RBM cells and to increase the success rate of titanium implants was evaluated. The nanoscale network structures formed by alkali etching markedly enhanced the cell adhesion and osteogenesis-related gene expression of RBM cells. Other cell behaviors, such as proliferation, alkaline phosphatase activity, osteocalcin deposition, and mineralization, were also markedly increased on heat-treated TNS-modified titanium. Our results suggest that nanostructure-modified titanium implants promote osteogenic differentiation, which may improve biointegration of these implants into alveolar bone.
2017年度
Persistent ID (NDL): info:ndljp/pid/12071582
https://dl.ndl.go.jp/pid/12071582
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2018-05-17
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000156/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp