Investigation of human papillomavirus infections and the expression of related genes in epithelial dysplasias and squamous cell carcinomas of the oral mucosa

The cover of this title could differ from library to library.

Available in National Diet Library

国立国会図書館デジタルコレクション

Digital data available

Check on the publisher's website

Investigation of human papillomavirus infections and the expression of related genes in epithelial dysplasias and squamous cell carcinomas of the oral mucosa

Persistent ID (NDL): info:ndljp/pid/12071583

Material type: 博士論文

Author: 上原, 行博

Publisher: -

Publication date: 2017-12-27

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use at the National Diet Library

本資料は、掲載誌(URI)等のリンク先にある学位授与機関のWebサイトやCiNii Dissertationsから、本文を自由に閲覧できる場合があります。

Notes on use

Note (General)：: We studied the prevalence of human papillomavirus (HPV) infections in patients with epithelial dysplasia and squamous cell carcinoma of the oral mucos...

Search by Bookstore

Read this material in an accessible format.

View materials in accessible formats for people with print disabilities (1Type)

Search by Bookstore

Read in Disability Resources

Other Services
- テキストデータ check it on 国立国会図書館デジタルコレクション

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Investigation of human papillomavirus infections and the expression of related genes in epithelial dysplasias and squamous cell carcinomas of the oral mucosa
Author/Editor: 上原, 行博
Author Heading: 上原, 行博
Publication Date: 2017-12-27
Publication Date (W3CDTF): 2017-12-27
Alternative Title: 口腔粘膜の上皮性異形成および扁平上皮癌におけるヒトパピローマウイルスの感染調査と関連因子の発現
Degree grantor/type: 大阪歯科大学
Date Granted: 2017-12-27
Date Granted (W3CDTF): 2017-12-27
Dissertation Number: 乙第1608号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 乙第1608号
Text Language Code: eng
Subject Heading: Human papillomavirus
Squamous cell carcinoma
Oral mucosa
p16
p53
Rb
Target Audience: 一般
Note (General): We studied the prevalence of human papillomavirus (HPV) infections in patients with epithelial dysplasia and squamous cell carcinoma of the oral mucosa, as well as the expression of p53, p53 (mutant type), Rb, p16, p21 and cyclin D1. The subjects were patients with irritation fibroma (IF), mild dysplasia (MiD), moderate dysplasia (MoD), severe dysplasia (SD), carcinoma in situ (CIS), well differentiated squamous cell carcinoma (WSCC) and poorly differentiated squamous cell carcinoma (PSCC) diagnosed at Osaka Dental University Hospital. Six patients, each with one of these conditions were examined. HPV was detected by in situ hybridization (ISH). Expression of p53, p53 (mutant type), Rb, p16, p21 and cyclin D1 was assessed by immunohistochemical staining (IHC). All cases were negative for HPV by ISH. For IHC, marked expression of p53 and mutant type p53 was seen in WSCC and PSCC. We could not detect expression of p21 in CIS, WSCC or PSCC. Marked expression of Rb and cyclin D1 was seen in CIS, WSCC and PSCC. We could not detect expression of p16 in WSCC or PSCC. The results suggested that HPV infections have low correlation with oral cancer. We found that p16 is a useful indicator of HPV infection.
2017年度
Persistent ID (NDL): info:ndljp/pid/12071583
https://dl.ndl.go.jp/pid/12071583
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2018-01-22
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000155/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp