Alternative Titleシステインプロテアーゼであるアクチニジンを含有したタブレットと舌ブラシを比較したときの舌背上細菌数減少について
Note (General)Tongue coating as an oral biofilm is responsible for 60% of all halitosis cases. It also in terferes with gustatory perception, and is associated with periodontal disease and pneu monia. As it is difficult to remove, the development of new cleaning methods is being promoted. We studied tablets containing actinidin, a cysteine protease, which has been reported to effectively remove this coating on the tongue. As tablets placed in the oral cavity are usually abraded by the tongue and palate to promote their dissolution, their ef fect in the elderly is likely to be reduced because of decreased motor function of the tongue. However, there is no literature discussing this effect in the elderly or comparing tablets with tongue brushes. To evaluate the efficacy of tablets containing actinidin on reducing the bacterial load on the tongue, we compared the effect of tablets, tongue brushes, and a combination of both on reduction of the bacterial load on the tongue. Tongue cleaning was performed for elderly individuals requiring assistance or care (the elderly group) and healthy young adults (the young group) using three methods : two tablets containing actinidin (the tablet method), brushing with a tongue brush (the brush ing method), and the combined use of both (the combined method). The bacterial load on the tongue dorsum was measured before treatment, immediately after treatment, and at 1 and 2 hours after treatment. With the brushing method, neither the elderly nor young groups showed significant changes in the bacterial load until 2 hours after treatment. In contrast, a marked decrease in the bacterial load was observed in both groups immedi ately after treatment using the tablets, and immediately after and at 2 hours after treat ment using the combined method. The tablets were particularly effective for the young group, and decreases in the bacterial load were observed immediately and at 1 hour after treatment when they were administered alone or in combination with the tongue brush. Furthermore, in the young group, the bacterial load immediately after and at 1 hour after treatment varied between the tablet and brushing methods. In contrast, in the elderly group, although the bacterial load was significantly reduced with the tablet method, this decrease was not observed when treatment was combined with the tongue brush. In both groups, the decrease in the bacterial load was more marked even at 2 hours after treatment when the combined use was compared with the brushing method alone. These results demonstrated that tablets containing cysteine pro tease are more effective than tongue brushes for reduction of the bacterial load, and that the effect lasts longer when the two methods are combined.
2016年度
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2022-02-06T04:33:19+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション