Alternative Titleエナメル質の微細亀裂に対する各種知覚過敏抑制材の封鎖性
Note (General)Purpose: With an increase in the number of remaining teeth per capita, the incidence of noncariogenic diseases other than dental caries and periodontal disease has been increasing. Among noncariogenic diseases, micro cracks of enamel (enamel cracks) may be a cause of hypersensitivity with no substance defect. The incidence of enamel cracks in healthy teeth was reported to exceed 95% in subjects aged 40 years or older. Considering sealing of enamel cracks with dentin desensitizers (desensitizers) based on their fast-acting property and convenience, we measured the permeation inhibition rate using a tooth model of hypersensitivity. At the same time, the influence of the storage condition on the permeation inhibition rate was also investigated by storing specimens in distilled water and remineralization solution. Methods: Enamel crack specimens were prepared with healthy bovine teeth with no dental caries. Using a device prepared following the method reported by Pashley et al., the specimen was connected to the device and the inner pressure was set at 25 mmHg. After application of each desensitizer, the enamel crack permeation inhibition rate was measured. After measurement, the specimens were stored in distilled water (DW group) or remineralization solution (RS group), and the enamel crack permeation inhibition rate was measured after 1 week and 1 month and 3 months. Results: The permeation inhibition rates at 1 month and 3 months were significantly higher than that immediately after application in the SS-, TD-, and NS-applied DW groups. In the SS- and NS-applied RS groups, the permeation inhibition rates at 1month and 3 months were significantly higher than that immediately after application. In the TD-applied RS group, the permeation inhibition rate at 3 months was significantly higher than that immediately after application. In the MS-applied DW and RS groups, the permeation inhibition rates at 1 week and 1 month and 3 months were significantly higher than that immediately after application. In the GP-applied DW and RS groups, a high sealing ability was noted from immediately after application, but the differences were not significant. Conclusion: It was suggested that although the timing of exhibiting the effect is different among the desensitizers, the effect is exhibited by repeated application.
2016年度
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2022-02-06T04:33:19+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション