Comparison of the bone forming ability of different sized-alpha tricalcium phosphate granules using a critical size defect model of the mouse calvaria

Persistent ID (NDL): info:ndljp/pid/12071626

Material type: 博士論文

Author: 徳田, 知子

Publisher: -

Publication date: 2016-03-11

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use at the National Diet Library

本資料は、掲載誌(URI)等のリンク先にある学位授与機関のWebサイトやCiNii Dissertationsから、本文を自由に閲覧できる場合があります。

Notes on use

Note (General)：: Alpha-tricalcium phosphate (α-TCP) has been investigated extensively as an artificial bone graft; however, the relationship between size of α-TCP part...

Search by Bookstore

Read this material in an accessible format.

View materials in accessible formats for people with print disabilities (1Type)

Search by Bookstore

Read in Disability Resources

Other Services
- テキストデータ check it on 国立国会図書館デジタルコレクション

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Comparison of the bone forming ability of different sized-alpha tricalcium phosphate granules using a critical size defect model of the mouse calvaria
Author/Editor: 徳田, 知子
Author Heading: 徳田, 知子
Publication Date: 2016-03-11
Publication Date (W3CDTF): 2016-03-11
Alternative Title: マウス頭蓋冠臨界骨欠損モデルを用いた粒径の異なるα型第三リン酸カルシウム顆粒の骨形成能の比較
Degree grantor/type: 大阪歯科大学
Date Granted: 2016-03-11
Date Granted (W3CDTF): 2016-03-11
Dissertation Number: 甲第784号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 甲第784号
Text Language Code: eng
Subject Heading: alpha tricalcium phosphate
bone formation
particle
calvaria
hydrolysis
Target Audience: 一般
Note (General): Alpha-tricalcium phosphate (α-TCP) has been investigated extensively as an artificial bone graft; however, the relationship between size of α-TCP particles and its bone-formation capability is not clear. In the present study, we compared the bone-formation capability of two different sized porous α-TCP particles (α-TCP200 [under 200 μm], and α-TCP600 [500–600 μm]) in critical-sized bone defects in mouse calvaria up to 12 wk after implantation. Scanning electron microscopy revealed that both particles possessed similar smooth surface with porous structure. Before implantation, inter-particle size and specific surface area of α-TCP200 were 27 μm and 0.40 m2/g and of α-TCP600 were 209 μm and 0.24m2/g, respectively. Histomorphometric analysis after implantation of the particles revealed that both particles promoted osteoconduction. At 12 wk, α-TCP200 induced superior bone formation than α-TCP600. At 4 wk, α-TCP200 showed more hydrolysis than α-TCP600. These results indicate that the size of α-TCP particles may influence their bone-formation capability in critical-sized bone defects of mouse calvaria. This effect might be partially due to the difference in the hydrolysis speed of different-sized particles.
2015
Persistent ID (NDL): info:ndljp/pid/12071626
https://dl.ndl.go.jp/pid/12071626
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2016-07-19
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000105/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp