Alternative Title骨梁間型骨転移と造血髄過形成の鑑別におけるFDG PETとChemical shift MRIの有用性の検討
Periodical titleJapanese Journal of Radiology
Degree grantor/typeNagasaki University (長崎大学)
Note (General)Purpose: To evaluate the utility of SUVmax on FDG-PET and chemical shift imaging (CSI) on MRI in the differentiation of intertrabecular metastasis (ITM) from hematopoietic bone marrow hyperplasia (HBMH).Patients and methods: We retrospectively evaluated 54 indeterminate focal bone marrow lesions in 44 patients detected on FDG-PET. The lesions were assigned to the metastasis group (M group, 29 lesions of 24 patients) and the non-metastasis group (non-M group, 25 lesions of 20 patients) based on the follow-up or the histopathological studies. The lesions were assessed with the maximum standardized uptake value (SUVmax) on FDG-PET CT images and signal change ratio (SCR) on CSI.Results: The median SUVmax were 5.62 and 2.91; the median SCR were − 0.08 and − 34.8 in M and non-M groups respectively, with significant difference (p < 0.001). With ROC curve analysis, the optimal cutoff value of SUVmax was 4.48 with a sensitivity of 72.4%, a specificity of 100%, and AUC of 0.905. The cutoff value of SCR was − 6.15 with a sensitivity of 82.8%, a specificity of 80%, and AUC of 0.818.Conclusion: FDG-PET and CSI on MRI are useful in distinguishing ITM from HBMH. Though their sensitivities are similar, the specificity of FDG-PET was higher than that of MRI.
長崎大学学位論文 学位記番号:博(医歯薬)甲第1381号 学位授与年月日:令和3年12月1日
Author: Nozomi Oki, Yohei Ikebe, Hirofumi Koike, Reiko Ideguchi, Daisuke Niino, Masataka Uetani
Citation: Japanese Journal of Radiology, 39, pp. 1077–1085; 2021
identifier:Nagasaki University (長崎大学), 博士(医学) (2021-12-01)
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開始ページ : 1077
終了ページ : 1085
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2022-03-06T04:54:00+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション