Obstructive sleep apnea syndrome as a potential cause of nocturia in younger adults

• Material Type: 博士論文
• Title: Obstructive sleep apnea syndrome as a potential cause of nocturia in younger adults
• Author/Editor: 宮内, 康行
• Author Heading: 宮内, 康行
• Publication Date: 2022-03-24
• Publication Date (W3CDTF): 2022-03-24
• Alternative Title: 若年成人における夜間頻尿の潜在的要因としての閉塞性睡眠時無呼吸症候群
• Degree grantor/type: 香川大学
• Date Granted: 2022-03-24
• Date Granted (W3CDTF): 2022-03-24
• Dissertation Number: 甲第806号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第806号
• Text Language Code: eng
• Alias of Author: Miyauchi, Yasuyuki
• Subject Heading: Adult; Age Factors; Aged; Female; Humans; Lower Urinary Tract Symptoms; Male; Middle Aged; Nocturia; Polysomnography; Prospective Studies; Quality of Life; Sleep Apnea, Obstructive; Sodium; Surveys and Questionnaires; Urinary Bladder, Overactive
• Target Audience: 一般
• Note (General): Objectives: To investigate the impact of age on the relationship between obstructive sleep apnea syndrome (OSAS), nocturia, and other lower urinary tract symptoms (LUTSs).; Methods: This was a secondary analysis study based on data derived from a previously conducted prospective observational cohort study on OSAS and nocturia. We analyzed 90 subjects who were suspected of having OSAS. Prior to polysomnography, we assessed International Prostate Symptom Score-Quality of Life scores, Overactive Bladder Symptom Scores, and International Consultation on Incontinence Modular Questionnaire-Nocturia Quality of Life scores to evaluate LUTSs. Nocturnal urine volume, night-time frequency, and night-time urine electrolyte content were measured during polysomnography. Patients were divided into groups according to age and OSAS severity determined using apnea-hypopnea index (AHI) scores. Young patients were those aged <65 years and elderly patients, ≥65 years. A multiple linear regression with multiple imputations was performed to examine the association of night-time frequency with demographic, polysomnographic, and clinical characteristics.; Results: In young patients, night-time frequency was significantly associated with nocturnal urine volume, AHI score, and total IPSS. However, night-time frequency in elderly subjects was not associated with demographic and polysomnographic characteristics. In order to compare the severity of OSAS, night-time frequency and urinary sodium content significantly increased only in young patients (P=.007 and .004, respectively).; Conclusion: OSAS is a strong candidate of causative factor for nocturia in younger individuals. When a younger patient complains nocturia without any urological disorders, OSAS should be kept in mind as a potential cause of nocturia.
• DOI: info:doi/10.1016/j.urology.2020.04.116; https://doi.org/info:doi/10.1016/j.urology.2020.04.116
• Persistent ID (NDL): info:ndljp/pid/12263384; https://dl.ndl.go.jp/pid/12263384
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-05-09T11:57:37+09:00
• Date Created (W3CDTF): 2022-04-22
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): https://kagawa-u.repo.nii.ac.jp/records/9558
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp