Gastrointestinal residue removal using a balloon overtube under ultrathin endoscopic navigation : Ex vivo and in vivo experimental studies

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Gastrointestinal residue removal using a balloon overtube under ultrathin endoscopic navigation : Ex vivo and in vivo experimental studies

Persistent ID (NDL): info:ndljp/pid/12263392

Material type: 博士論文

Author: 小塚, 和博

Publisher: -

Publication date: 2022-03-24

Material Format: Digital

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Name of awarding university/degree: 香川大学,博士（医学）

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Note (General)：: Pooled gastric residues involving blood clots and food interrupt appropriate endoscopic intervention, leading to poor outcomes in endoscopic hemostasi...

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Material Type: 博士論文
Title: Gastrointestinal residue removal using a balloon overtube under ultrathin endoscopic navigation : Ex vivo and in vivo experimental studies
Author/Editor: 小塚, 和博
Author Heading: 小塚, 和博
Publication Date: 2022-03-24
Publication Date (W3CDTF): 2022-03-24
Alternative Title: ダブルバルーン内視鏡用オーパーチューブを用いた細径内視鏡ガイド下胃内残渣除去法 : Ex vivoと In vivoでの研究
Degree grantor/type: 香川大学
Date Granted: 2022-03-24
Date Granted (W3CDTF): 2022-03-24
Dissertation Number: 甲第798号
Degree Type: 博士（医学）
Conferring No. (Dissertation): 甲第798号
Text Language Code: eng
Alias of Author: Kozuka, Kazuhiro
Subject Heading: gastrointestinal residue
endoscopic removal
gastrointestinal bleeding
balloon overtube
Target Audience: 一般
Note (General): Pooled gastric residues involving blood clots and food interrupt appropriate endoscopic intervention, leading to poor outcomes in endoscopic hemostasis and lifesaving. However, procedures and devices that enable the effective removal of gastrointestinal residues remain unsatisfactory. This study aimed to evaluate the efficacy and safety of our developed suction method in ex vivo and in vivo studies. We created a hand-made device with a large suction diameter, consisting of a balloon overtube and an ultrathin endoscope for navigation. In the ex vivo study, we compared the success rate and the suctioning time for four types of simulated residue between a standard endoscope and our device. Our device had s significantly higher suction ability and a shorter procedure time than the standard endoscope. The subsequent in vivo animal study involved five beagle dogs that were administered with food jelly to mimic gastric residue. Suction was performed twice for five dogs (ten attempts). The outcome measure was the successful procedure rate; secondary outcomes were procedure-associated complications and procedure time. The procedure was successful in all attempts, without any complications. The mean procedure time was 5 min. This novel method enabled the efficient and safe removal of gastric residue, and our findings will likely lead to the development of the instrument.
DOI: info:doi/10.3390/jcm10173796
https://doi.org/info:doi/10.3390/jcm10173796
Persistent ID (NDL): info:ndljp/pid/12263392
https://dl.ndl.go.jp/pid/12263392
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-05-09T11:57:37+09:00
Date Created (W3CDTF): 2022-04-21
Format (IMT): PDF
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): https://kagawa-u.repo.nii.ac.jp/records/9549
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp