Current Prevalence of Oral Helicobacter pylori among Japanese Adults Determined Using a Nested Polymerase Chain Reaction Assay

• Material Type: 博士論文
• Title: Current Prevalence of Oral Helicobacter pylori among Japanese Adults Determined Using a Nested Polymerase Chain Reaction Assay
• Author/Editor: Nagata, Ryoko
• Author Heading: Nagata, Ryoko
• Publication Date: 2021-03-23
• Publication Date (W3CDTF): 2021-03-23
• Alternative Title: Nested PCRアッセイ法による日本人の口腔Helicobacter pyloriの検出率
• Degree grantor/type: 新潟大学
• Date Granted: 2021-03-23
• Date Granted (W3CDTF): 2021-03-23
• Dissertation Number: 甲第4862号
• Degree Type: 博士（歯学）
• Conferring No. (Dissertation): 甲第4862号
• Text Language Code: eng
• Alias of Author: 永田, 量子
• Subject Heading: Helicobacter pylori; oral cavity; nested polymerase chain reaction (PCR); prevalence; characteristic distribution
• Target Audience: 一般
• Note (General): In Japan, gastric Helicobacter pylori infection prevalence has markedly decreased with socioeconomic development. We aimed to investigate the prevalence of oral H. pylori in Japanese adults in 2020 by sex, age, sampling site, and medical history. Unstimulated saliva, supragingival biofilm, and tongue coating were obtained from 88 subjects-with no complaints of upper digestive symptoms-attending a dentist's office for dental check-up or disorders. Supragingival biofilm was collected from the upper incisors, lower incisors, upper right molars and lower left molars to analyze the characteristic distribution. Oral H. pylori was detected using nested polymerase chain reaction. Oral H. pylori prevalence did not statistically differ by sex or age. Supragingival biofilm (30.7%) was the most common oral H. pylori niche; it was also detected in 4.5% of saliva and 2.3% of tongue samples. The lower incisor was the most common site among the supragingival biofilm samples, followed by the upper incisors, lower left molars, and upper right molars. Oral H. pylori DNA was frequently detected in patients with a history of gastric H. pylori infection. Oral H. pylori has a characteristic distribution independent of sex and age, suggesting that it is part of the normal microflora in the adult oral cavity.; Pathogens. 2021, 10(1), 10.; 新大院博(歯)第470号
• Persistent ID (NDL): info:ndljp/pid/12263518; https://dl.ndl.go.jp/pid/12263518
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-05-09T11:57:37+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10191/0002000358; https://niigata-u.repo.nii.ac.jp/records/2000358
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp