Effects of Surface Modification on Adsorption Behavior of Cell and Protein on Titanium Surface by Using Quartz Crystal Microbalance System

• Material Type: 博士論文
• Title: Effects of Surface Modification on Adsorption Behavior of Cell and Protein on Titanium Surface by Using Quartz Crystal Microbalance System
• Author/Editor: 松本, 卓巳
• Author Heading: 松本, 卓巳
• Publication Date: 2022-03-04
• Publication Date (W3CDTF): 2022-03-04
• Alternative Title: QCMシステムを用いたチタン表面への細胞とタンパク質の吸着挙動に及ぼす表面処理の影響
• Degree grantor/type: 大阪歯科大学
• Date Granted: 2022-03-04
• Date Granted (W3CDTF): 2022-03-04
• Dissertation Number: 甲第918号
• Degree Type: 博士（歯学）
• Conferring No. (Dissertation): 甲第918号
• Text Language Code: eng
• Subject Heading: titanium｜UV-treatment ｜atmospheric pressure plasma-treatment｜ QCM measurement｜ ROS assay
• Target Audience: 一般
• Note (General): Primary stability and osseointegration are major challenges in dental implant treatments, where the material surface properties and wettability are critical in the early formation of hard tissue around the implant. In this study, a quartz crystal microbalance (QCM) was used to measure the nanogram level amount of protein and bone marrow cells adhered to the surfaces of titanium (Ti) surface in real time. The effects of ultraviolet (UV) and atmospheric-pressure plasma treatment to impart surface hydrophilicity to the implant surface were evaluated. The surface treatment methods resulted in a marked decrease in the surface carbon (C) content and increase in the oxygen (O) content, along with super hydrophilicity. The results of QCM measurements showed that adhesion of both adhesive proteins and bone marrow cells was enhanced after surface treatment. Although both methods produced implants with good osseointegration behavior and less reactive oxidative species, the samples treated with atmospheric pressure plasma showed the best overall performance and are recommended for clinical use. It was verified that QCM is an effective method for analyzing the initial adhesion process on dental implants.; 2021年度
• Persistent ID (NDL): info:ndljp/pid/12296878; https://dl.ndl.go.jp/pid/12296878
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-06-05T18:01:14+09:00
• Date Created (W3CDTF): 2022-05-13
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://id.nii.ac.jp/1392/00000295/
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp