Histopathological evaluation of cesarean scar defect in women with cesarean scar syndrome

• Material Type: 博士論文
• ISSN: 1447-0578
• Title: Histopathological evaluation of cesarean scar defect in women with cesarean scar syndrome
• Volume: 21 1
• Author/Editor: 樋口, 明日香; HIGUCHI, Asuka
• Author Heading: 樋口, 明日香; HIGUCHI, Asuka
• Publication, Distribution, etc.: Wiley
• Publication Date: 2021-12-21
• Publication Date (W3CDTF): 2021-12-21
• Periodical title: Reproductive medicine and biology.
• Degree grantor/type: 滋賀医科大学
• Date Granted: 2022-03-10
• Date Granted (W3CDTF): 2022-03-10
• Dissertation Number: 乙第476号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 乙第476号
• Text Language Code: eng
• Subject Heading: cesarean section; endometriosis; endometrium; infertility; inflammation
• Target Audience: 一般
• Note (General): pdf; Purpose:To explore the histopathological findings of cesarean scar defect (CSD) and the immunological component in women with cesarean scar syndrome (CSS).; Methods:This retrospective study was conducted in a university hospital and a public hospital. A total of 63 patients with secondary infertility due to CSS who underwent laparoscopic resection of the CSD lesion were enrolled (CSS group), and 21 patients who underwent hysterectomy with a history of cesarean section were enrolled as control (non-CSS group). We compared the differences in histopathological findings of CSD lesions by hematoxylin and eosin staining and immunohistochemistry for CD3, CD20, CD56, CD68, CD138, myeloperoxidase, and tryptase between the two groups.; Results:The frequency of presence of endometrium on the CSD surface was significantly lower (p = 0.0023) and that of adenomyosis was significantly higher (p = 0.0195) in the CSS group than in the non-CSS group. The number of CD3-, CD20-, CD68-, and tryptase-positive cells was significantly lower in the CSS group than in the non-CSS group; however, the number of CD138-positive cells was significantly higher in the CSS group (p = 0.0042).; Conclusions:This study suggested that the absence of endometrium, presence of adenomyosis, and chronic inflammation in CSD contributes to secondary infertility due to CSS.; Thesis or Dissertation; 令和3年度; 10.1002/rmb2.12431; 博士論文要旨
• DOI: info:doi/10.1002/rmb2.12431; https://doi.org/info:doi/10.1002/rmb2.12431
• Persistent ID (NDL): info:ndljp/pid/12304049; https://dl.ndl.go.jp/pid/12304049
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-07-05T02:30:21+09:00
• Date Created (W3CDTF): 2022-06-16
• Format (IMT): PDF; application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Related Material (URI): http://hdl.handle.net/10422/00013356
• Periodical Title (URI): http://hdl.handle.net/10422/00013355; https://shiga-med.repo.nii.ac.jp/records/4271
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-09-07 再収集