Impact of abdominal aortic calcification on 90-day mortality in sepsis patients: a pilot retrospective cohort study

• Material Type: 博士論文
• ISSN: 2052-8817
• Title: Impact of abdominal aortic calcification on 90-day mortality in sepsis patients: a pilot retrospective cohort study
• Volume: 8 1
• Author/Editor: 加藤, 隆之; KATO, Takayuki
• Author Heading: 加藤, 隆之; KATO, Takayuki
• Publication, Distribution, etc.: Wiley
• Publication Date: 2021-01-25
• Publication Date (W3CDTF): 2021-01-25
• Periodical title: Acute Medicine & Surgery.
• Degree grantor/type: 滋賀医科大学
• Date Granted: 2022-03-10
• Date Granted (W3CDTF): 2022-03-10
• Dissertation Number: 乙第472号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 乙第472号
• Text Language Code: eng
• Subject Heading: Abdominal aorta; mortality; prognosis; sepsis; vascular calcification
• Target Audience: 一般
• Note (General): pdf; Aim:We aimed to investigate the association between aortic calcification and 90-day mortality in sepsis patients admitted to the intensive care unit.; Methods:We evaluated adult patients (≥18 years) diagnosed with sepsis based on the Sepsis-3 criteria and admitted to our intensive care unit between April 2011 and March 2015. They were classified according to the degree of abdominal aortic calcification (severe and non-severe), grouped per age (<65, 65-75, and >75 years), and matched. Survival curves were generated, and between-group differences were evaluated.; Results:Overall, 164 patients were included. The Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores were not significantly different between the severity groups, whereas there were significant differences in age (P < 0.001), sex (P = 0.017), and presence of diabetes mellitus (P < 0.001), hypertension (P < 0.001), dyslipidemia (P = 0.048), and maintenance dialysis (P = 0.001). The severe abdominal aortic calcification group showed significantly poorer prognosis than the non-severe group (log-rank P = 0.009). The adjusted odds ratio of severe calcification was the highest in patients aged <65 years (7.167; 95% confidence interval, 1.042-49.28, P = 0.045). Twenty-eight patients from each group were matched. The 90-day survival rate of the severe calcification group remained significantly lower than that of the non-severe calcification group (53.6% [15/28] versus 82.1% [23/28], P = 0.022).; Conclusions:Severe abdominal aortic calcification is associated with the 90-day mortality of sepsis patients, particularly among those aged <65 years. Thus, caution is necessary in patients younger than 65 years; they may need to be treated with as much care as the elderly.; Thesis or Dissertation; 令和3年度; 10.1002/ams2.630; 博士論文要旨
• DOI: info:doi/10.1002/ams2.630; https://doi.org/info:doi/10.1002/ams2.630
• Persistent ID (NDL): info:ndljp/pid/12304051; https://dl.ndl.go.jp/pid/12304051
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-07-05T02:30:21+09:00
• Date Created (W3CDTF): 2022-06-15
• Format (IMT): PDF; application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Related Material (URI): http://hdl.handle.net/10422/00013350
• Periodical Title (URI): http://hdl.handle.net/10422/00013349; https://shiga-med.repo.nii.ac.jp/records/4265
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-09-08 再収集