An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity

• Material Type: 博士論文
• Title: An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity
• Author/Editor: 若井, 恵里
• Author Heading: 若井, 恵里
• Publication, Distribution, etc.: 三重大学
• Publication Date: 2022-03-25
• Publication Date (W3CDTF): 2022-03-25
• Degree Grantor: 三重大学
• Date Granted: 2022-03-25
• Date Granted (W3CDTF): 2022-03-25
• Dissertation Number: 甲医学第2114号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医学第2114号
• Text Language Code: eng
• Subject Heading: cisplatin; nephrotoxicity; drug repositioning; data-driven approach; gene expression signature; adverse events; zebrafish
• Target Audience: 一般
• Note (General): application/pdf; 本文/Department of Integrative Pharmacology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan; 13p
• Persistent ID (NDL): info:ndljp/pid/12313674; https://dl.ndl.go.jp/pid/12313674
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-08-08T06:02:54+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Related Material (URI): https://doi.org/10.3390/ph13120480
• Periodical Title (URI): http://hdl.handle.net/10076/00020580
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

• Summary, etc.: Cisplatin is widely used to treat various types of cancers, but it is often limited by nephrotoxicity. Here, we employed an integrated in silico and i...