Predictive factor of recurrence after endoscopic papillectomy for ampullary neoplasms 7

• Material Type: 博士論文
• ISSN: 1868-6974
• Title: Predictive factor of recurrence after endoscopic papillectomy for ampullary neoplasms
• Volume: 28 7
• Author/Editor: 髙橋, 孝輔
• Author Heading: 髙橋, 孝輔
• Publication, Distribution, etc.: John Wiley and Sons Inc
• Publication Date: 2022-06-01
• Publication Date (W3CDTF): 2022-06-01
• Alternative Title: 十二指腸乳頭部腫瘍に対する内視鏡的乳頭部切除術後の再発予測因子
• Periodical title: Journal of Hepato-Biliary-Pancreatic Sciences
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2022-06-01
• Date Granted (W3CDTF): 2022-06-01
• Dissertation Number: 甲医歯薬第1457号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医歯薬第1457号
• Text Language Code: eng
• Subject Heading: adenocarcinoma; ampullary; ampullary adenoma; endoscopic papillectomy; recurrence
• Target Audience: 一般
• Note (General): Background/Purpose: Recurrence of ampullary neoplasms after endoscopic papil-lectomy (EP) has not been well elucidated. This study aimed to clarify the predictive factors for recurrences after EP. We also aimed to investigate the retreatment of the recurrent lesions and their outcomes.Methods: This multicenter, retrospective cohort study included 96 patients with am-pullary neoplasms who underwent EP at four tertiary centers between January 2000 and October 2018.Results: The pathological diagnoses of resected specimens confirmed adenoma in 62 and adenocarcinoma in 34 patients (six Tis, 24 T1a, three T1b, one inconclu-sive). Complete resection was confirmed for 79 patients (82.3%). Recurrent lesions were observed in 13 patients (13.5%) during a median follow- up of 3 months (1- 36 months) after EP. The predictive factors of recurrence were piecemeal resection, and non- negative horizontal or vertical margin in univariate analysis. Non- negative vertical margin was the only independent predictive factor of recurrence in the mul-tivariate analysis. The recurrent lesions were treated endoscopically in 11 patients. Recurrence after the endoscopic retreatments was observed in one patient.Conclusions: Complete resection with negative vertical margin is an important fac-tor in preventing the recurrence of ampullary neoplasms after EP. Endoscopic re-treatments are also feasible for recurrent lesions.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1457号 学位授与年月日:令和4年6月1日; Author: Takahashi Kosuke, Ozawa Eisuke, Yasuda Ichiro, Komatsu Naohiro, Miyaaki Hisamitsu, Ohnita Ken, Yamao Takuji, Oba Kazuo, Ichikawa Tatsuki, Nakao Kazuhiko; Citation: Journal of Hepato-Biliary-Pancreatic Sciences, 28(7), pp.625-634; 2022; identifier:Nagasaki University (長崎大学), 博士(医学) (2022-06-01); http://hdl.handle.net/10069/00041587
• DOI: info:doi/10.1002/jhbp.992; https://doi.org/info:doi/10.1002/jhbp.992
• Persistent ID (NDL): info:ndljp/pid/12313714; https://dl.ndl.go.jp/pid/12313714
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-08-08T06:02:54+09:00
• Date Created (W3CDTF): 2022-07-15
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
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• Availability of remote photoduplication service: 可
• Related Material (URI): http://hdl.handle.net/10069/00041587
• Periodical Title (URI): http://hdl.handle.net/10069/00041621
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp