Association between serum 25-hydroxyvitamin D and physical performance measures in middle-aged and old Japanese men and women：The Unzen study

• Material Type: 博士論文
• Title: Association between serum 25-hydroxyvitamin D and physical performance measures in middle-aged and old Japanese men and women：The Unzen study
• Author/Editor: 小島（内山）, 迪子
• Author Heading: 小島（内山）, 迪子
• Publication, Distribution, etc.: PLOS
• Publication Date: 2022-09-30
• Publication Date (W3CDTF): 2022-09-30
• Alternative Title: 日本人中高年男女における血清25ヒドロキシビタミンDとフィジカルパフォーマンスとの関連：雲仙スタディ
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2022-09-30
• Date Granted (W3CDTF): 2022-09-30
• Dissertation Number: 甲共医歯薬第27号
• Degree Type: 博士(医学)
• Text Language Code: eng
• Target Audience: 一般
• Note (General): Purpose: Regarding epidemiological studies, the role of vitamin D in musculoskeletal functionality (muscle weakness and physical performance) among elderly people is still controversial. The purpose of the present study was to investigate the associations between 25-hydroxyvitamin D [25(OH)D] and physical performance among community-dwelling middle-aged and old Japanese men and women.Methods: The subjects were community-dwelling 297 men and 415 women aged 50 years and over. Data on height (m) and weight (kg) were collected. Serum 25(OH)D, parathyroid hormone, calcium, and albumin levels were measured. Serum 25(OH)D was classified into deficiency group: < 20 ng/mL, insufficiency group: 20–30 ng/mL, and sufficiency group: ≧ 30 ng/mL. Physical performance was assessed by grip strength, chair stand time, and functional reach. Information on current smoking, alcohol drinking, regular exercise, any comorbidities (hypertension, heart disease, diabetes mellitus, lung disease, and stroke), and pain (lumbar and knee) was collected.Results: Vitamin D deficiency and insufficiency based on serum 25(OH)D levels were observed in 15.2% and 56.9% of men and 52.0% and 43.6% of women, respectively. In men, higher serum 25(OH)D levels were associated with better grip strength (p for trend = 0.003), chair stand time (p for trend = 0.042), and functional reach (p for trend <0.001). On the other hand, these parameters were not associated with serum 25(OH)D levels in women.Conclusion: A higher level of serum 25(OH)D was associated with better physical performance in men but not in women.; 長崎大学学位論文 学位記番号:共博(医歯薬)甲第27号 学位授与年月日:令和4年9月30日; Author: Michiko Uchiyama, Satoshi Mizukami, Kazuhiko Arima, Takayuki Nishimura, Yoshihito Tomita, Yasuyo Abe, Natsumi Tanaka, Yuzo Honda, Hisashi Goto, Maiko Hasegawa, Youko Sou, Ritsu Tsujimoto, Mitsuo Kanagae, Makoto Osaki, Kiyoshi Aoyagi; Citation: PLoS ONE, 16(12), art.no. e0261639; 2021; identifier:Nagasaki University (長崎大学), 博士(医学) (2022-09-30); http://hdl.handle.net/10069/00041840
• Persistent ID (NDL): info:ndljp/pid/12651193; https://dl.ndl.go.jp/pid/12651193
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• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2023-03-02T11:18:09+09:00
• Format (IMT): application/pdf
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• Periodical Title (URI): http://hdl.handle.net/10069/00041872
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp