Alternative Title地域在住住民のメンタルヘルスと骨量低下の関連；長崎アイランド研究における骨の健康に関する研究
Degree grantor/typeNagasaki University (長崎大学)
Note (General)Osteoporosis and its related fractures are important public health issues. This study examined the association between the Kessler Psychological Distress Scale (K6) and low bone mass in middle-aged community-dwelling men and women. A crosssectional study was nested in a prospective observational study of 1,101 participants (median age: 57 [49-62] years in men and 58 [50-62] years in women) residing in a rural city in western Japan. Participants were recruited during medical check-ups in 2016 and 2017 from the community-dwelling population. The bone mass of the calcaneus was evaluated using quantitative ultrasound. Of the participants, 56 men (14.9%) and 144 women (19.9%) had a bone mass of less than 70% of the mean of young adults. Univariate analysis revealed that there was a trend toward lower body mass index (BMI) and higher prevalence of low bone mass with an increase in K6 scores in men but not in women. Logistic regression analysis, adjusting for possible confounders (age, BMI, smoking, drinking habits, exercise habits, diabetes, hyperlipidemia, and hypertension), showed significant associations between the K6 scores and low bone mass (odds ratio (OR) = 2.66 for the men with 5 to 12 points of K6, OR = 7.51 for men with ≥ 13 of K6, not for women). We showed an association between psychological distress and low bone mass independent of cofounders among community-dwelling middle-aged men but not women. This suggests that healthy mental health in middle-aged men may be a possible target for the prevention of consequent osteoporosis or fragile bone fractures.
長崎大学学位論文 学位記番号:共博(医歯薬)甲第30号 学位授与年月日:令和5年3月20日
Author: Tetsuji Okawachi, Kazuhiko Arima, Satoshi Mizukami, Serina Koto, Masahiro Suiko, Ayano Kit, Hiroki Nakashima, Michiko Uchiyama, Yuzo Honda, Natsumi Tanaka, Ritsu Tsujimoto, Takayuki Nishimura, Yoshihito Tomita, Yasuyo Abe, Yosuke Kusano, Shin-Ya Kawashiri, Mami Tamai, Hirotomo Yamanashi, Yasuhiro Nagata, Atsushi Kawakami, Takahiro Maeda, Kiyoshi Aoyagi
Citation: Acta Medica Nagasakiensia, 66(2), pp. 81-86; 2023
identifier:Nagasaki University (長崎大学), 博士(医学) (2023-03-20)
http://hdl.handle.net/10069/00042276
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2023-05-05T22:12:35+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション