Umami taste sensitivity is associated with food intake and oral environment in subjects with diabetes

• Material Type: 博士論文
• Title: Umami taste sensitivity is associated with food intake and oral environment in subjects with diabetes
• Author/Editor: Kawakami, Ayuka; Bando, Mika; Takashi, Tomoe; Sugiuchi, Mizuki; Hyodo, Mizusa; Mishima, Yuna; Kuroda, Masashi; Mori, Hiroyasu; Kuroda, Akio; Yumoto, Hiromichi; Matsuhisa, Munehide; Sakaue, Hiroshi; Tsutsumi, Rie
• Author Heading: Kawakami, Ayuka; Bando, Mika; Takashi, Tomoe; Sugiuchi, Mizuki; Hyodo, Mizusa; Mishima, Yuna; Kuroda, Masashi; Mori, Hiroyasu; Kuroda, Akio; Yumoto, Hiromichi; Matsuhisa, Munehide; Sakaue, Hiroshi; Tsutsumi, Rie
• Publication, Distribution, etc.: Tokushima University Faculty of Medicine
• Publication Date: 2023-02
• Publication Date (W3CDTF): 2023-02
• Alternative Title: 糖尿病患者におけるうま味味覚感度は食品摂取と口腔内環境に関連する; Umami taste sensitivity in diabetes
• Degree grantor/type: 徳島大学
• Date Granted: 2023-03-23
• Date Granted (W3CDTF): 2023-03-23
• Dissertation Number: 甲第3708号
• Degree Type: 博士（栄養学）
• Text Language Code: eng
• Subject Heading: Umami; taste sensitivity; Diabetes; Food intake; Oral environments
• Target Audience: 一般
• Note (General): Objective : Dysgeusia is a serious problem in patients with diabetes because it often leads to overeating, which is associated with disease progression. This study aimed to investigate the association between taste sensitivity, eating habits, and the oral environment. Subjects and methods : In this cross-sectional study of 75 subjects with diabetes, gustatory function was assessed using the whole-mouth method, and lingual taste receptor gene expression was measured by real-time PCR. Food intake was evaluated using a food frequency questionnaire based on food groups. The oral environment was assessed using xerostomia and periodontal comprehensive examination. Results : In total, 45.3%, 28.0%, and 18.7% of subjects showed lower umami taste sensitivity, low sweet taste sensitivity, and low salt taste sensitivity, respectively. Lower umami sensitivity correlated with lower estimated glomerular filtration rate and higher energy-source food intake. Subjects with diabetes with higher plaque control record showed significantly higher T1R3 gene expression than those with lower plaque control record. Conclusion : Reduced umami taste sensitivity is associated with decreased renal function and high energy food intake in diabetes. Subjects with diabetes with higher plaque control record showed significantly higher T1R3 gene expression, suggesting that the oral environment affects taste gene expression.
• Persistent ID (NDL): info:ndljp/pid/12886304; https://dl.ndl.go.jp/pid/12886304
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2023-06-02T22:06:11+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/118208
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp