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博士論文

Association between resistance-associated NS5A variants of hepatitis C virus and efficacy of direct-acting antivirals in human hepatocyte transplanted mice 1) Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice 2) Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

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Association between resistance-associated NS5A variants of hepatitis C virus and efficacy of direct-acting antivirals in human hepatocyte transplanted mice 1) Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice 2) Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

Persistent ID (NDL)
info:ndljp/pid/12887067
Material type
博士論文
Author
寺岡, 雄吏
Publisher
-
Publication date
2019-09-20
Material Format
Digital
Capacity, size, etc.
-
Name of awarding university/degree
広島大学,博士(医学),Doctor of Philosophy in Medical Science
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Notes on use

Note (General):

Biochemical and Biophysical Research Communications 500 (2018) 152e157Teraoka et al., Journal of General Virology 2018;99:1058-1065

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Digital

Material Type
博士論文
Author/Editor
寺岡, 雄吏
Author Heading
Publication Date
2019-09-20
Publication Date (W3CDTF)
2019-09-20
Alternative Title
ヒト肝細胞キメラマウスを用いたNS5A阻害薬耐性変異型HCVとDAA療法の関連性の研究 1) NS5A阻害薬治療不成功例におけるNS5A耐性関連変異およびヒト肝細胞キメラマウスを用いたNS5A-P32欠失変異を持つC型肝炎ウイルスに対する有効な治療法の検討 2) NS5A阻害薬治療不成功例におけるダクラタスビル/アスナプレビル/ベクラブビル治療の問題点について
Degree grantor/type
広島大学
Date Granted
2019-09-20
Date Granted (W3CDTF)
2019-09-20