Severe Complications after General Anesthesia versus Sedation during Pediatric Diagnostic Cardiac Catheterization for Ventricular Septal Defect

• Material Type: 博士論文
• Title: Severe Complications after General Anesthesia versus Sedation during Pediatric Diagnostic Cardiac Catheterization for Ventricular Septal Defect
• Author/Editor: Ogawa, Yuki; Yamana, Hayato; Noda, Tatsuya; Kishimoto, Miwa; Yoshihara, Shingo; Kanaoka, Koshiro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Kawaraguchi, Masahiko; Imamura, Tomoaki
• Author Heading: Ogawa, Yuki; Yamana, Hayato; Noda, Tatsuya; Kishimoto, Miwa; Yoshihara, Shingo; Kanaoka, Koshiro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Kawaraguchi, Masahiko; Imamura, Tomoaki
• Publication, Distribution, etc.: MDPI
• Publication Date: 2022-08-31
• Publication Date (W3CDTF): 2022-08-31
• Alternative Title: 心室中隔欠損症に対する小児心臓カテーテル検査における麻酔方法と重症合併症の関連
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2023-03-15
• Date Granted (W3CDTF): 2023-03-15
• Dissertation Number: 甲第867号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: cardiac catheterization; anesthesia; ventricular septal defect
• Target Audience: 一般
• Note (General): type:Thesis; Pediatric cardiac catheterization requires unconsciousness and immobilization throughgeneral anesthesia or sedation. This study aimed to compare the occurrence of severe complicationsin pediatric diagnostic cardiac catheterization for ventricular septal defect between general anesthesiaand sedation performed under similar institutional environments. Using the Japanese DiagnosisProcedure Combination database, we retrospectively identified pediatric patients (aged <2years) who underwent diagnostic cardiac catheterization for ventricular septal defect between July2010 and March 2019. The composite outcome was the occurrence of severe complications, includingcatecholamine use and intensive care unit admission, within seven days after catheterization.Overlap weighting based on propensity scores was used to adjust for patient- and hospital-levelconfounding factors. We identified 3159 patients from 87 hospitals, including 930 under generalanesthesia and 2229 under sedation. The patient- and hospital-level baseline characteristics differedbetween the groups. After adjustment, the proportion of patients with severe complications wassignificantly higher in the general anesthesia group than in the sedation group (2.4% vs. 0.6%; riskdifference, 1.8% [95% confidence interval, 0.93–2.6%]). Severe complications occurred more frequentlyin the general anesthesia group than in the sedation group. Further research on anestheticmethods is necessary to assess the safety and accuracy of pediatric diagnostic cardiac catheterization.; 博士（医学）・甲第867号・令和5年3月15日; © 2022 by the authors. Licensee MDPI, Basel, Switzerland.This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).; identifier:Journal of clinical medicine Vol.11 No.17 Article No.5165 (2022 Aug); identifier:20770383; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4099; identifier:Journal of clinical medicine, 11(17): Article No.5165
• Persistent ID (NDL): info:ndljp/pid/13120257; https://dl.ndl.go.jp/pid/13120257
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• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2023-12-05T21:41:08+09:00
• Format (IMT): application/pdf
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• Periodical Title (URI): http://hdl.handle.net/10564/4099
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