Impact of Olfactory Change on Postoperative Body Weight Loss in Patients with Gastric Cancer after Gastrectomy

• Material Type: 博士論文
• Title: Impact of Olfactory Change on Postoperative Body Weight Loss in Patients with Gastric Cancer after Gastrectomy
• Author/Editor: Matsuo, Hiromi; Matsui, Ryota; Kumagai, Koshi; Ida, Satoshi; Saino, Yoko; Fujihara, Aya; Takagi, Kumi; Itami, Yukiko; Ishii, Misuzu; Moriya, Naoki; Izumi-Mishima, Yuna; Nomura, Kazuhiro; Tsutsumi, Yasuo M.; Nunobe, Souya; Tsutsumi, Rie; Sakaue, Hiroshi
• Author Heading: Matsuo, Hiromi; Matsui, Ryota; Kumagai, Koshi; Ida, Satoshi; Saino, Yoko; Fujihara, Aya; Takagi, Kumi; Itami, Yukiko; Ishii, Misuzu; Moriya, Naoki; Izumi-Mishima, Yuna; Nomura, Kazuhiro; Tsutsumi, Yasuo M.; Nunobe, Souya; Tsutsumi, Rie; Sakaue, Hiroshi
• Publication, Distribution, etc.: MDPI
• Publication Date: 2024-03-15; 16 6
• Publication Date (W3CDTF): 2024-03-15
• Alternative Title: 胃がん患者における嗅覚変化が胃切除後の体重減少に与える影響
• Degree grantor/type: 徳島大学
• Date Granted: 2024-04-25
• Date Granted (W3CDTF): 2024-04-25
• Dissertation Number: 甲第3829号
• Degree Type: 博士（栄養学）
• Text Language Code: eng
• Subject Heading: olfaction; gastric cancer; gastrectomy; body weight loss; smell
• Target Audience: 一般
• Note (General): Patients undergoing gastrectomy for gastric cancer may experience alterations in olfaction, yet the association between olfactory changes and postoperative weight loss remains uncertain. This study aimed to elucidate the relationship between olfactory changes and postoperative weight loss in patients with gastric cancer. Patients who underwent radical gastrectomy for gastric cancer between February 2022 and August 2022 were included in the study. Those experiencing a higher Visual Analog Scale (VAS) score postoperatively compared to preoperatively were deemed to have undergone olfactory changes. Postoperative weight loss was determined using the 75th percentile as a cutoff value, designating patients surpassing this threshold as experiencing significant weight loss. Multivariate logistic regression analysis was employed to identify risk factors for postoperative weight loss, with statistical significance set at p < 0.05. Out of 58 patients, 10 (17.2%) exhibited olfactory changes. The rate of postoperative weight loss at one month was markedly higher in the group with olfactory changes compared to those without (9.6% versus 6.2%, respectively; p = 0.002). In addition, the group experiencing olfactory changes demonstrated significantly lower energy intake compared to the group without such changes (1050 kcal versus 1250 kcal, respectively; p = 0.029). Logistic regression analysis revealed olfactory changes as an independent risk factor for significant weight loss at one month postoperatively (odds ratio: 7.64, 95% confidence interval: 1.09–71.85, p = 0.048). In conclusion, olfactory changes emerged as an independent risk factor for postoperative weight loss at one month in patients with gastric cancer following gastrectomy.
• Persistent ID (NDL): info:ndljp/pid/13722794; https://dl.ndl.go.jp/pid/13722794
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2024-07-05T22:07:00+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/119382
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp