Preliminary observations on the associations between sensory processing abnormalities and event-related potentials in adults with autism spectrum disorder

• Material Type: 博士論文
• Title: Preliminary observations on the associations between sensory processing abnormalities and event-related potentials in adults with autism spectrum disorder
• Author/Editor: Mizui, Ryo; Yamamuro, Kazuhiko; Okazaki, Kosuke; Uratani, Mitsuhiro; Kashida, Natsuko; Ishida, Rio; Makinodan, Manabu
• Author Heading: Mizui, Ryo; Yamamuro, Kazuhiko; Okazaki, Kosuke; Uratani, Mitsuhiro; Kashida, Natsuko; Ishida, Rio; Makinodan, Manabu
• Publication, Distribution, etc.: Wiley Open Access
• Publication Date: 2024-02; 3 1
• Publication Date (W3CDTF): 2024-02
• Alternative Title: 自閉スペクトラム症の成人における感覚処理異常と事象関連電位との関連についての予備的観察
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2024-06-26
• Date Granted (W3CDTF): 2024-06-26
• Dissertation Number: 甲第929号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: autism spectrum disorder; event‐related potential; N100; sensory processing
• Target Audience: 一般
• Note (General): type:Thesis; Aim: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is thought to involve a variety of neurophysiological characteristics. Event-related potentials (ERPs) reflect cognitive functions in the brain's cognitive processing. In this study, we investigated differences in P300 and N100 of ERPs between ASD and typically developing groups and focused on the relationship between the components of ERPs and measures of autistic traits and sensory processing characteristics. Methods: ERPs were measured in 96 subjects in the ASD group and 62 subjects in the age- and sex-adjusted typically developing group. Correlations between each component and the scores of the Autism-Spectrum Quotient Japanese version (AQ-J) and the Adolescent and Adult Sensory Profile (AASP) were also evaluated. Results: The ASD group showed a significant decrease in the amplitude of N100 at C3. Furthermore, a negative correlation was found between lower amplitude at C3 of N100 and low registered sensory scores in both groups. Conclusion: Our findings imply that the N100 amplitude at C3 could be a potential indicator for examining the neurophysiological traits of ASD; however, these results should be interpreted with caution due to their preliminary nature. These tentative insights into sensory processing anomalies may be discernible in specific subsets of the ASD population, providing a foundation for future investigative pathways.; 権利情報：© 2024 The Authors. Psychiatry and Clinical Neurosciences Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.; identifier:Psychiatry and Clinical Neurosciences Reports. 2024 Feb, vol.3, no.1, article no.e173; identifier:2769-2558; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4386; identifier:Psychiatry and Clinical Neurosciences Reports, 3(1): e173
• Persistent ID (NDL): info:ndljp/pid/13730984; https://dl.ndl.go.jp/pid/13730984
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2024-08-02T22:09:18+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10564/4386
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp