Comparison of Quality of Recovery between Modified Thoracoabdominal Nerves Block through Perichondrial Approach versus Oblique Subcostal Transversus Abdominis Plane Block in Patients Undergoing Total Laparoscopic Hysterectomy: A Pilot Randomized Controlled Trial

• Material Type: 博士論文
• Title: Comparison of Quality of Recovery between Modified Thoracoabdominal Nerves Block through Perichondrial Approach versus Oblique Subcostal Transversus Abdominis Plane Block in Patients Undergoing Total Laparoscopic Hysterectomy: A Pilot Randomized Controlled Trial
• Author/Editor: Suzuka, Takanori; Tanaka, Nobuhiro; Kadoya, Yuma; Ida, Mitsuru; Iwata, Masato; Ozu, Naoki; Kawaguchi, Masahiko
• Author Heading: Suzuka, Takanori; Tanaka, Nobuhiro; Kadoya, Yuma; Ida, Mitsuru; Iwata, Masato; Ozu, Naoki; Kawaguchi, Masahiko
• Publication, Distribution, etc.: MDPI
• Publication Date: 2024-01; 13 3
• Publication Date (W3CDTF): 2024-01
• Alternative Title: 腹腔鏡下子宮全摘出術における、M-TAPAと肋骨弓下斜角腹横筋膜面ブロックの回復の質の比較：パイロット無作為化比較試験
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2024-09-27
• Date Granted (W3CDTF): 2024-09-27
• Dissertation Number: 甲第937号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: nerve block; pain management; pain; postoperative period; postoperative complications; regional anesthesia
• Target Audience: 一般
• Note (General): type:Thesis; Modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA) provides a wide analgesic range. Herein, we examined the quality of recovery (QoR) of M-TAPA for total laparoscopic hysterectomy (TLH) compared with oblique subcostal transversus abdominis plane block (OSTAPB) and measured plasma levobupivacaine concentrations (PClevo). Forty female patients undergoing TLH were randomized to each group. Nerve blocks were performed bilaterally with 25 mL of 0.25% levobupivacaine administered per side. The primary outcome was changes in QoR-15 scores on postoperative days (POD) 1 and 2 from the preoperative baseline. The main secondary outcomes were PClevo at 15, 30, 45, 60, and 120 min after performing nerve block. Group differences (M-TAPA-OSTAPB) in mean changes from baseline in QoR-15 scores on POD 1 and 2 were -11.3 (95% confidence interval (CI), -24.9 to 2.4, p = 0.104; standard deviation (SD), 22.8) and -7.0 (95% CI, -20.5 to 6.6, p = 0.307; SD, 18.7), respectively. Changes in PClevo were similar in both groups. The post hoc analysis using Bayesian statistics revealed that posterior probabilities of M-TAPA being clinically more effective than OSTAPB were up to 22.4 and 24.4% for POD 1 and 2, respectively. In conclusion, M-TAPA may not be superior to OSTAPB for TLH.; 権利情報：© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).; identifier:Journal of Clinical Medicine. 2024 Jan, vol.13, no.3, article no.712; identifier:2077-0383; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4413; identifier:Journal of Clinical Medicine, 13(3): 712
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• Date Accepted (W3CDTF): 2024-11-12T17:29:51+09:00
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• Periodical Title (URI): http://hdl.handle.net/10564/4413
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