Clinical Factors Associated with SFTS Diagnosis and Severity in Cats

• Material Type: 博士論文
• Title: Clinical Factors Associated with SFTS Diagnosis and Severity in Cats
• Author/Editor: 許, 強
• Author Heading: 許, 強
• Publication, Distribution, etc.: MDPI
• Publication Date: 2024-09-20; 16 6
• Publication Date (W3CDTF): 2024-09-20
• Alternative Title: 猫のSFTS診断と重症度に関連する臨床的要因
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2024-09-20
• Date Granted (W3CDTF): 2024-09-20
• Dissertation Number: 甲医歯薬第1646号
• Degree Type: 博士(医学)
• Text Language Code: eng
• Subject Heading: severe fever thrombocytopenia syndrome; cat; biomarkers; prognosis factors; veterinarian
• Target Audience: 一般
• Note (General): Severe fever with thrombocytopenia syndrome (SFTS) is a potentially fatal tick-borne zoonosis caused by SFTS virus (SFTSV). In addition to tick bites, animal-to-human transmission of SFTSV has been reported, but little is known about feline SFTSV infection. In this study, we analyzed data on 187 cats with suspected SFTS to identify biomarkers for SFTS diagnosis and clinical outcome. Body weight, red and white blood cell and platelet counts, and serum aspartate aminotransferase and total bilirubin levels were useful for SFTS diagnosis, whereas alanine aminotransferase, aspartate aminotransferase and serum SFTSV RNA levels were associated with clinical outcome. We developed a scoring model to predict SFTSV infection. In addition, we performed a phylogenetic analysis to reveal the relationship between disease severity and viral strain. This study provides comprehensive information on feline SFTS and could contribute to the protection of cat owners, community members, and veterinarians from the risk of cat-transmitted SFTSV infection.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1646号 学位授与年月日:令和6年9月20日; Author: Hiromu Osako, Qiang Xu, Takeshi Nabeshima, Jean Claude Balingit, Khine Mya Nwe, Fuxun Yu, Shingo Inoue, Daisuke Hayasaka, Mya Myat Ngwe Tun, Kouichi Morita and Yuki Takamatsu; Citation: Viruses, 16(6), art. no. 874; 2024; Nagasaki University (長崎大学), 博士(医学) (2024-09-20)
• Persistent ID (NDL): info:ndljp/pid/13873247; https://dl.ndl.go.jp/pid/13873247
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2024-12-06T22:41:13+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10069/0002001554
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp