The impact of obstructive sleep apnea syndrome on nocturnal urine production in older men with nocturia. 4

• Material Type: 博士論文
• ISSN: 0090-4295
• Title: The impact of obstructive sleep apnea syndrome on nocturnal urine production in older men with nocturia.
• Volume: 84 4
• Author/Editor: Hoshiyama, Fumiaki; Hirayama, Akihide; Tanaka, Masahiro; Taniguchi, Mitsutaka; Ohi, Motoharu; Momose, Hitoshi; Nakamura, Takahito; Ogawa, Shuhei; Torimoto, Kazumasa; Tanaka, Nobumichi; Fujimoto, Kiyohide
• Author Heading: Hoshiyama, Fumiaki; Hirayama, Akihide; Tanaka, Masahiro; Taniguchi, Mitsutaka; Ohi, Motoharu; Momose, Hitoshi; Nakamura, Takahito; Ogawa, Shuhei; Torimoto, Kazumasa; Tanaka, Nobumichi; Fujimoto, Kiyohide
• Publication, Distribution, etc.: Elsevier Science
• Publication Date: 2014-10; 84 4
• Publication Date (W3CDTF): 2014-10
• Alternative Title: 高齢夜間頻尿患者における夜間尿産生に対する閉塞性睡眠時無呼吸症候群の影響
• Periodical title: Urology
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2014-12-03
• Date Granted (W3CDTF): 2014-12-03
• Dissertation Number: 乙第1349号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 乙第1349号
• Text Language Code: eng
• Target Audience: 一般
• Note (General): type:Thesis; OBJECTIVE:To investigate the impact of obstructive sleep apnea syndrome (OSAS) on night-time secretion of brain natriuretic peptide (BNP) and antidiuretic hormone (ADH) in older men with nocturia accompanied by nocturnal polyuria.MATERIALS AND METHODS:One hundred six men with nocturia aged ≥ 60 years underwent full-night polysomnography to determine whether they had OSAS. Blood count, standard chemistry panel, BNP, urinary ADH, urinary creatinine (u-Cre), and urinary osmolarity were measured at 6:00 AM, and a frequency volume chart was recorded on the same day that polysomnography was performed.RESULTS:We evaluated 83 patients after excluding 18 with mild OSAS and 5 with nocturnal polyuria index <0.35. Participants with OSAS had higher apnea-hypopnea index (P < .0001) than those without OSAS. Body mass index and systolic blood pressure were higher in OSAS patients than those in the control group. BNP was higher in the OSAS patients than in the control patients (48.6 ± 41.4 vs 30.7 ± 31.5; P = .0006). On urinalysis, OSAS patients showed higher urinary sodium and u-Cre secretion than controls (24.7 ± 11.3 vs 16.2 ± 5.1; P <.0001). Urine osmolarity was also higher in OSAS patients than in the control patients (616 ± 172 vs 516 ± 174; P = .0285). There was no significant difference in urinary ADH and u-Cre (6.7 ± 10.4 vs 6.8 ± 7.8; P = .3617) between the 2 groups.CONCLUSION:Our results indicated that older men with nocturnal polyuria and OSAS did not compensate their fluid imbalance presented with decreased secretion of ADH but increased BNP level.; 博士（医学）・乙第1349号・平成26年12月3日; Copyright © 2014 Elsevier Inc. All rights reserved.; identifier:Urology Vol.84 No.4 p.892-896; identifier:00904295; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2753; identifier:Urology, 84(4): 892-896
• DOI: info:doi/10.1016/j.urology.2014.02.073; https://doi.org/info:doi/10.1016/j.urology.2014.02.073
• Persistent ID (NDL): info:ndljp/pid/8953112; https://dl.ndl.go.jp/pid/8953112
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Available (W3CDTF): 2015-03-03
• Date Accepted (W3CDTF): 2015-02-03T05:25:05+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10564/2753
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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