Augmentation Index does not Reflect the Risk of Coronary Artery Disease in Elderly Patients 5

• Material Type: 博士論文
• ISSN: 1347-4820
• Title: Augmentation Index does not Reflect the Risk of Coronary Artery Disease in Elderly Patients
• Volume: 78 5
• Author/Editor: Hayashi, Shuji; Yamada, Hirotsugu; Bando, Mika; Hotchi, Junko; Ise, Takayuki; Yamaguchi, Koji; Iwase, Takashi; Soeki, Takeshi; Wakatsuki, Tetsuzo; Tamaki, Toshiaki; Sata, Masataka
• Author Heading: Hayashi, Shuji; Yamada, Hirotsugu; Bando, Mika; Hotchi, Junko; Ise, Takayuki; Yamaguchi, Koji; Iwase, Takashi; Soeki, Takeshi; Wakatsuki, Tetsuzo; Tamaki, Toshiaki; Sata, Masataka
• Publication, Distribution, etc.: The Japanese Circulation Society
• Publication Date: 2014-02-24; 78 5
• Publication Date (W3CDTF): 2014-02-24
• Alternative Title: Augmentation indexは高齢者の冠動脈疾患のリスクを評価し得ない; Augmentation Index in CAD
• Periodical title: Circulation Journal
• Degree grantor/type: 徳島大学
• Date Granted: 2014-03-24
• Date Granted (W3CDTF): 2014-03-24
• Dissertation Number: 甲第2670号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第2670号
• Text Language Code: eng
• Subject Heading: Arterial stiffness; Augmentation index; Central blood pressure; Coronary artery disease
• Target Audience: 一般
• Note (General): Background: Augmentation index (AI) has been used as a clinical index of arterial stiffness and has been reported to be an independent predictor of cardiovascular events, but some investigators have reported that AI is not a useful marker to identify coronary artery disease (CAD) in elderly patients. The majority of CAD patients are elderly people, therefore the aim of this study was to examine whether AI is a useful marker to identify the risk of CAD.Methods and Results: A total of 120 patients (69±10 years of age; 83 male) who underwent cardiac catheterization for suspected CAD were enrolled. Invasive central blood pressure (BP) was measured using a fluid-filled catheter. Non-invasive AI was calculated by the SphygmoCor (AtCor Medical) system at the end of catheterization. Subjects consisted of 99 patients with CAD and 21 patients without CAD. There was no significant difference in AI between the CAD and the non-CAD groups (24±10 vs. 24±14%). Non-invasive systolic central BP was lower than the invasive systolic central BP (115±18 vs. 130±23 mmHg, P<0.001) in all patients. Non-invasive diastolic central BP was greater than the invasive diastolic central BP (67±10 vs. 63±10 mmHg, P<0.001).Conclusions: In elderly patients, AI may not be a useful marker to identify CAD.
• DOI: info:doi/10.1253/circj.CJ-13-1422; https://doi.org/info:doi/10.1253/circj.CJ-13-1422
• Persistent ID (NDL): info:ndljp/pid/9550197; https://dl.ndl.go.jp/pid/9550197
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2015-12-01T13:36:39+09:00
• Format (IMT): application/pdf
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• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/106070
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp