Dose-volume constrained optimization in intensity-modulated radiation therapy treatment planning

• Material Type: 博士論文
• ISSN: 1029-242X
• Title: Dose-volume constrained optimization in intensity-modulated radiation therapy treatment planning
• Volume: 2015
• Author/Editor: Tanaka, Yoshihiro; Fujimoto, Ken'ichi; Yoshinaga, Tetsuya
• Author Heading: Tanaka, Yoshihiro; Fujimoto, Ken'ichi; Yoshinaga, Tetsuya
• Publication, Distribution, etc.: Springer nature
• Publication Date: 2015-04-08
• Publication Date (W3CDTF): 2015-04-08
• Alternative Title: 強度変調放射線治療計画の線量体積制約に基づく最適化
• Periodical title: Journal of Inequalities and Applications
• Degree grantor/type: 徳島大学
• Date Granted: 2015-10-15
• Date Granted (W3CDTF): 2015-10-15
• Dissertation Number: 甲第2885号
• Degree Type: 博士（保健学）
• Conferring No. (Dissertation): 甲第2885号
• Text Language Code: eng
• Subject Heading: intensity-modulated radiation therapy treatment planning; dose-volume constraints; dose-volume constrained optimization; inverse problem; stability of solution
• Target Audience: 一般
• Note (General): We present a novel optimization method to handle dose-volume constraints (DVCs) directly in intensity-modulated radiation therapy (IMRT) treatment planning based on the idea of continuous dynamical methods. Most of the conventional methods are constructed for solving inconsistent inverse problems with, e.g., dose-volume based objective functions, and one expects to obtain a feasible solution that minimally violates the DVCs. We introduce the concept of ‘acceptable’, meaning that there exists a nonempty set of radiation beam weights satisfying the given DVCs, and we resolve the issue that the objective and evaluation are different in the conventional planning approach. We apply the initial-value problem of the proposed dynamical system to an acceptable and inconsistent inverse problem and prove that the convergence to an equilibrium in the acceptable set of solutions is theoretically guaranteed by using the Lyapunov theorem. Indeed, we confirmed that we can obtain acceptable beam weights through numerical experiments using phantom data simulating a clinical setup for an acceptable and inconsistent IMRT planning system.
• DOI: info:doi/10.1186/s13660-015-0643-2; https://doi.org/info:doi/10.1186/s13660-015-0643-2
• Persistent ID (NDL): info:ndljp/pid/9550438; https://dl.ndl.go.jp/pid/9550438
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2015-12-01T13:36:39+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
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• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/109514
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp