Magnetic resonance imaging shrinkage patterns following neoadjuvant chemotherapy for breast carcinomas with an emphasis on the radiopathological correlations. 5

• Material Type: 博士論文
• ISSN: 2049-9450
• Title: Magnetic resonance imaging shrinkage patterns following neoadjuvant chemotherapy for breast carcinomas with an emphasis on the radiopathological correlations.
• Volume: 2 5
• Author/Editor: TOMIDA, Kaori
• Author Heading: TOMIDA, Kaori
• Publication, Distribution, etc.: Spandidos Publications
• Publication Date: 2014-06-30
• Publication Date (W3CDTF): 2014-06-30
• Periodical title: Molecular and Clinical Oncology
• Degree grantor/type: 滋賀医科大学
• Date Granted: 2015-09-09
• Date Granted (W3CDTF): 2015-09-09
• Dissertation Number: 甲第737号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第737号
• Text Language Code: eng
• Subject Heading: magnetic resonance imaging; neoadjuvant chemotherapy; shrinkage pattern; breast cancer
• Target Audience: 一般
• Note (General): Preoperative neoadjuvant chemotherapy (NAC) is considered to be the standard treatment for locally-advanced breast carcinomas. Obtaining precise information regarding the tumor extent and distribution by imaging modalities to assess the success of breast-conserving surgery following NAC is extremely important. Analysis of the detailed radiopathological correlation of magnetic resonance imaging (MRI) following NAC has not been reported previously. The MRI and histopathological shrinkage patterns of residual breast carcinomas in 27 consecutive cases were analyzed following NAC and classified into five categories: Types I and II (concentric shrinkage with and without surrounding lesions, respectively); type III (shrinkage with residual multinodular lesions); type IV (diffuse contrast enhancement in whole quadrant); and non-visualization. The present study clearly demonstrated that the most common MRI shrinkage pattern was type I (11 cases), followed by type II and non-visualization, and the most common histopathological shrinkage pattern was type II (11 cases), followed by type III (8 cases). The concordance rate between MRI and pathological patterns was 48% and the worst concordance MRI pattern was type I. MRI is considered to be a useful method for evaluation of the residual carcinoma following NAC. However, the concordance rate was low in the MRI pattern I cases and tiny foci of residual carcinoma were present in half of the non-visualization cases, as shown by MRI. Therefore, the tumor extent must be completely resected for patients who undergo NAC, and postoperative radiation may be important for preventing local recurrence of breast carcinoma.; Thesis or Dissertation; 平成27年度; 10.3892/mco.2014.333; 出版社サイト
• DOI: info:doi/10.3892/mco.2014.333; https://doi.org/info:doi/10.3892/mco.2014.333
• Persistent ID (NDL): info:ndljp/pid/9550898; https://dl.ndl.go.jp/pid/9550898
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2015-12-01T13:36:39+09:00
• Date Created (W3CDTF): 2017-02-17
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Original Material (URI): https://dx.doi.org/10.3892/mco.2014.333
• Periodical Title (URI): http://hdl.handle.net/10422/10973; https://shiga-med.repo.nii.ac.jp/records/2918
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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