海馬記憶回路網のパターン分離における小脳の役割

• Material Type: 博士論文
• Title: 海馬記憶回路網のパターン分離における小脳の役割
• Author/Editor: 城間, 綾乃; Shiroma, Ayano
• Author Heading: 城間, 綾乃; Shiroma, Ayano
• Publication, Distribution, etc.: University of the Ryukyus
• Publication Date: 2015-10-06
• Publication Date (W3CDTF): 2015-10-06
• Alternative Title: Cerebellar contribution to pattern separation of human hippocampal memory circuits
• Periodical title: The Cerebellum
• Pages: 1-18
• ISSN (Periodical Title): 14734222
• Degree Grantor: 琉球大学
• Date Granted: 2015-12-18
• Date Granted (W3CDTF): 2015-12-18
• Dissertation Number: 甲第442号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 医研第442号
• Text Language Code: eng
• Subject Heading: Posterior lateral cerebellum; Cognitive function; Brain tumor; Memory; Hippocampus; fMRI
• Target Audience: 一般
• Note (General): The cerebellum is a crucial structure for cognitive function as well as motor control. Benign brain tumors such as schwannomas, meningiomas, and epidermoids tend to occur in the cerebellopontine angle cisterns and may cause compression of the posterior lateral cerebellum near the superior posterior fissure, where the eloquent area for cognitive function was recently identified. The present study examined cognitive impairment in patients with benign cerebellar tumors before and after surgical intervention in order to clarify the functional implications of this region in humans. Patients with cerebellar tumors showed deficits in psychomotor speed and working memory compared with healthy controls. Moreover, these impairments were more pronounced in patients with right cerebellar tumors. Functional magnetic resonance imaging during performance of a lure task also demonstrated that cerebellar tumors affected pattern separation or the ability to distinguish similar experiences of episodic memory or events with discrete, non-overlapping representations, which is one of the important cognitive functions related to the hippocampus. The present findings indicate that compression of the human posterior lateral cerebellum affects hippocampal memory function.; 学位論文
• Persistent ID (NDL): info:ndljp/pid/9969170; https://dl.ndl.go.jp/pid/9969170
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2016-05-01T16:38:40+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Related Material (URI): https://doi.org/10.1007/s12311-015-0726-0
• Periodical Title (URI): http://hdl.handle.net/20.500.12000/33565
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

Table of Contents

2017-05-03 再収集

2017-05-03 再収集

2017-05-03 再収集

2021-06-01 再収集

2021-06-01 再収集