Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies

• Material Type: 記事
• Title: Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
• Author Heading: Junko Iwano; Daisuke Shinmi; https://orcid.org/0000-0001-6706-0030; Kazuhiro Masuda; Takashi Murakami; Junichi Enokizono; https://orcid.org/0009-0006-8898-835x
• Publication Date: 2019-11
• Publication Date (W3CDTF): 2019-11
• Periodical title: Drug Metabolism and Disposition
• No. or year of volume/issue: 47 11
• Volume: 47
• Issue: 11
• Pages: 1240-1246
• Publication date of volume/issue (W3CDTF): 2019-11
• ISSN (Periodical Title): 00909556
• Publication (Periodical Title): Elsevier BV
• Subject Heading: Male; Mice, Inbred BALB C; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoembryonic Antigen; Mice; Liver; Area Under Curve; Animals
• Target Audience: 一般
• Standard No. (Other): PMID : 31533926
• DOI: 10.1124/dmd.119.088179
• Date Created (W3CDTF): 2019-09-18
• Access Restrictions: インターネット公開
• Rights (production): https://www.elsevier.com/tdm/userlicense/1.0/; https://www.elsevier.com/legal/tdmrep-license
• Related Material (URI): https://api.elsevier.com/content/article/PII:S0090955624077110?httpAccept=text/xml; https://api.elsevier.com/content/article/PII:S0090955624077110?httpAccept=text/plain; https://syndication.highwire.org/content/doi/10.1124/dmd.119.088179
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• Data Provider (Database): 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• Original Data Provider (Database): Crossref; https://www.crossref.org; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja

• Summary, etc.: Carcinoembryonic antigen (CEA) is a tumor-specific antigen overexpressed in multiple cancers. CEA is expressed as a membrane protein, a part of which ...