Associations of carotid atherosclerosis and hyperuricemia with height in relation to drinking status of rural Japanese men: The Nagasaki Islands study.

• Material Type: 博士論文
• ISSN: 0001-6055
• Title: Associations of carotid atherosclerosis and hyperuricemia with height in relation to drinking status of rural Japanese men: The Nagasaki Islands study.
• Volume: 59 3
• Author/Editor: 佐藤, 晋平
• Author Heading: 佐藤, 晋平
• Publication, Distribution, etc.: 長崎大学医学部
• Publication Date: 2017-03-21
• Publication Date (W3CDTF): 2017-03-21
• Alternative Title: 日本人男性における、身長と飲酒の状況を加味した動脈硬化と高尿酸血症の関連
• Periodical title: Acta Medica Nagasakiensia
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2017-03-21
• Date Granted (W3CDTF): 2017-03-21
• Dissertation Number: 甲医歯薬第917号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医歯薬第917号
• Text Language Code: eng
• Subject Heading: carotid atherosclerosis; hyperuricemia; height; drinking status; men
• Target Audience: 一般
• Note (General): Background; Several studies have identified a positive, independent association between uric acid and atherosclerosis whereas uric acid was once considered to be a major antioxidant in human plasma with possible beneficial anti-atherosclerotic effects. Several other studies have found an inverse association between height and stroke, while a previous study of ours detected a positive association between height and hyperuricemia. However, even though uric acid levels may be strongly affected by alcohol consumption and serum creatinine, no published study has examined the possible associations between hyperuricemia and carotid atherosclerosis while taking both height and drinking status into account. Methods; We conducted a cross-sectional study of 1,337 men aged 30-89 years undergoing a general health check-up toinvestigate the associations of hyperuricemia and carotid atherosclerosis with height in relation to drinking status. Results; Of the total study population, 312 men were diagnosed with carotid atherosclerosis (carotid intima-media thickness (CIMT) ?1.1 mm) and 365 men with hyperuricemia (serum uric acid>7.0mg/dL). For shorter non-drinkers, a significantly positive association between these two abnormalities was detected, which was independent of classical cardiovascular risk factors except for serum creatinine. However, this association ceased to exist after further adjustment for serum creatinine. However, while the age-adjusted model showed no significant association for taller drinkers, adjustment for serum creatinine produced a significantly inverse association. Conclusion; Our study established that hyperuricemia is associated with carotid atherosclerosis for Japanese men, whilebody height, drinking status and serum creatinine are important determining factors for this association.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第917号 学位授与年月日:平成29年3月21日; Author: Shimpei Sato, Yuji Shimizu, Naomi Hayashida, Mako Nagayoshi, Jun Koyamatsu, Hirotomo Yamanashi, Koichiro Kadota, Mio Nakazato, Keita Inoue, Noboru Takamura, Yoshiyuki Oozono, Takahiro Maeda; Citation: Acta Medica Nagasakiensia, 59(3), pp.77-82; 2015; Nagasaki University (長崎大学), 博士(医学) (2017-03-21)
• Persistent ID (NDL): info:ndljp/pid/10318922; https://dl.ndl.go.jp/pid/10318922
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2017-04-02T16:10:31+09:00
• Date Created (W3CDTF): 2020-12-21
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10069/37089; https://nagasaki-u.repo.nii.ac.jp/records/3898
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2021-03-07 再収集