Influence of dietary intake of fish oil, magnesium and zinc on metabolic parameters among individuals tested for diabetes

• Material Type: 博士論文
• Title: Influence of dietary intake of fish oil, magnesium and zinc on metabolic parameters among individuals tested for diabetes
• Author/Editor: Takagi, Hisayo
• Author Heading: Takagi, Hisayo
• Publication, Distribution, etc.: 三重大学
• Publication Date: 2015-07-15
• Publication Date (W3CDTF): 2015-07-15
• Degree grantor/type: 三重大学
• Date Granted: 2015-07-15
• Date Granted (W3CDTF): 2015-07-15
• Dissertation Number: 甲医学第1737号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医学第1737号
• Text Language Code: eng
• Alias of Author: タカギ, ヒサヨ; 髙木, 久代
• Subject Heading: docosahexaenoic; eicosapentaenoic; polyunsaturated fatty acids; insulinresistance; renal function
• Target Audience: 一般
• Note (General): application/pdf; Background and Aims: The present study aimed to assess the significance and degree of correlation between intake of fish oil, magnesium (Mg), and zinc (Zn) and metabolic parameters.Methods: Correlation coefficients among nutrient intake and physical and laboratory parameters were determined using Spearman’s rho (ρ) test or a multiple regression model among Japanese individuals (male:female, 37:66; median age, 55 years) who completed a semi- quantitative food questionnaire and underwent diabetes tests. Individuals with diabetes were excluded. Results: Spearman’s test revealed several weak but significant correlations between intake of fish oil including ω-3 polyunsaturated fatty acids (PUFA) and various metabolic parameters. The test showed that Zn intake in women significantly correlated with reduced systolic blood pressure (SBP), alanine aminotransferase (ALT), γ-glutamyl transpeptidase (γ-GTP), and homeostasis model assessment-insulin resistance (HOMA-R). Multivariate analysis revealed that intake of fish oil, eicosapentaenoic acid (EPA), and Zn was significantly associated with increased serum levels of high-density lipoprotein cholesterol (HDL-C) (fish oil vs. HDL-C, p/95%CI =0.0438/0.0055 to 0.3724; EPA vs. HDL-C, 0.0439/0.0053 to 0.3724; Zn vs. HDL-C, 0.0041/0.0890 to 0.4609). Multivariate analysis revealed that ω-3 PUFA was associated with decreased serum ALT levels (0.0240/-5.000 to -0.0367) and that Zn correlated with SBP (0.0239/-0.5149 to -0.0377) in women.Conclusion: Intake of fish oil, Mg, and Zn was associated with some metabolic parameters. Abundant intake of fish oil including ω-3 PUFA and Zn can exert anti-arteriosclerotic effects through increasing serum levels of HDL-C. Omega-3 PUFA can reduce liver inflammation and Zn reduced systolic blood pressure in women.; 本文 / 三重大学大学院医学系研究科 生命医科学専攻 病態制御医学講座 消化器内科学分野; 28p
• DOI: info:doi/10.1016/j.nut.2015.02.019; https://doi.org/info:doi/10.1016/j.nut.2015.02.019
• Persistent ID (NDL): info:ndljp/pid/11526693; https://dl.ndl.go.jp/pid/11526693
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-08-11T22:41:34+09:00
• Date Created (W3CDTF): 2020-07-29
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10076/00019132; https://mie-u.repo.nii.ac.jp/records/13514
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-12-15 再収集