Unique hemoglobin dynamics in female Tibetan highlanders
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DOI[10.1186/s41182-020-00289-6]to the data of the same series
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- Material Type
- 記事
- Author/Editor
- Hiroaki ArimaMasayuki NakanoSweta Koirala
- Publication, Distribution, etc.
- Publication Date
- 2021-01-04
- Publication Date (W3CDTF)
- 2021-01-04
- Periodical title
- Tropical medicine and health
- No. or year of volume/issue
- 49(2)
- Volume
- 49(2)
- ISSN (Periodical Title)
- 1349-4147
- ISSN-L (Periodical Title)
- 1348-8945
- Text Language Code
- eng
- DOI
- 10.1186/s41182-020-00289-6
- Persistent ID (NDL)
- info:ndljp/pid/11667859
- Collection
- Collection (Materials For Handicapped People:1)
- Collection (particular)
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
- Acquisition Basis
- オンライン資料収集制度
- Date Accepted (W3CDTF)
- 2021-04-28T11:35:34+09:00
- Date Captured (W3CDTF)
- 2021-04-28
- Format (IMT)
- application/pdf
- Access Restrictions
- 国立国会図書館内限定公開
- Service for the Digitized Contents Transmission Service
- 図書館・個人送信対象外
- Availability of remote photoduplication service
- 可
- Periodical Title (URI)
- Periodical Title (Persistent ID (NDL))
- info:ndljp/pid/11667857
- Data Provider (Database)
- 国立国会図書館 : 国立国会図書館デジタルコレクション
- Summary, etc.
- Background: Tibetan highlanders have adapted to hypoxic environments through the development of unique mechanisms that suppress an increase in hemoglobin (Hb) concentration even in high-altitude areas. Hb concentrations generally decrease with increasing age. However, in the highlands, chronic altitude sickness is known to occur in the elderly population. To investigate how aging in a hypoxic environment affects Hb levels in Tibetan highlanders, we focused on the Mustang people, who live above 3500 m. We tried to clarify the pure relationship between aging and Hb levels in a hypoxic environment.Results: We found that the Hb concentration increased with increasing age in females but not in males. Multivariate analysis showed that age, pulse pressure, the poverty index, and vascular diameter were strongly correlated with the Hb concentration. Conclusions: We found unique Hb dynamics among female Tibetan highlanders. As seen in these Hb dynamics, there may be sex-based differences in the adaptive mechanism in Tibetan highlanders.Tropical Medicine and Health, 49(1), art.no.2; 2020
- DOI
- 10.1186/s41182-020-00289-6
- Access Restrictions
- インターネット公開
- Rights (production)
- © 2021, The Author(s). Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you giveappropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate ifchanges were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- Related Material (URI)
- Is Referenced By
- Sex differences in genotype frequency and the risk of polycythemia associated with rs13419896 and rs2790859 among Tibetan highlanders living in Tsarang, Mustang, NepalHigh prevalence of rheumatoid arthritis and its risk factors among Tibetan highlanders living in Tsarang, Mustang district of NepalIndividual variations and sex differences in hemodynamics and percutaneous arterial oxygen saturation (SpO2) in Tibetan highlanders of Tsarang in the Mustang district of Nepal
- References
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- 国立情報学研究所 : CiNii Research
- Original Data Provider (Database)
- 学術機関リポジトリデータベース雑誌記事索引データベースCrossrefCiNii Articles科学研究費助成事業データベース科学研究費助成事業データベースCrossrefCrossrefCrossref
- Bibliographic ID (NDL)
- 11667859
- NAID
- 120006956200