Unique hemoglobin dynamics in female Tibetan highlanders

• Material Type: 博士論文
• Title: Unique hemoglobin dynamics in female Tibetan highlanders
• Volume: 49
• Author/Editor: 有馬, 弘晃
• Author Heading: 有馬, 弘晃
• Publication, Distribution, etc.: BioMed Central Ltd
• Publication Date: 2021-03-22
• Publication Date (W3CDTF): 2021-03-22
• Alternative Title: チベット高地民の女性における特異なヘモグロビン動態
• Periodical title: Tropical Medicine and Health
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2021-03-22
• Date Granted (W3CDTF): 2021-03-22
• Dissertation Number: 甲医歯薬第1343号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医歯薬第1343号
• Text Language Code: eng
• Target Audience: 一般
• Note (General): Background: Tibetan highlanders have adapted to hypoxic environments through the development of unique mechanisms that suppress an increase in hemoglobin (Hb) concentration even in high-altitude areas. Hb concentrations generally decrease with increasing age. However, in the highlands, chronic altitude sickness is known to occur in the elderly population. To investigate how aging in a hypoxic environment affects Hb levels in Tibetan highlanders, we focused on the Mustang people, who live above 3500 m. We tried to clarify the pure relationship between aging and Hb levels in a hypoxic environment.Results: We found that the Hb concentration increased with increasing age in females but not in males. Multivariate analysis showed that age, pulse pressure, the poverty index, and vascular diameter were strongly correlated with the Hb concentration.Conclusions: We found unique Hb dynamics among female Tibetan highlanders. As seen in these Hb dynamics, there may be sex-based differences in the adaptive mechanism in Tibetan highlanders.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1343号 学位授与年月日:令和3年3月22日; Author: Hiroaki Arima, Masayuki Nakano, Sweta Koirala, Hiromu Ito, Basu Dev Pandey, Kishor Pandey, Takayuki Wada & Taro Yamamoto; Citation: Tropical Medicine and Health, 49, art.no.2; 2021; identifier:Nagasaki University (長崎大学), 博士(医学) (2021-03-22); http://hdl.handle.net/10069/00040612
• DOI: info:doi/10.1186/s41182-020-00289-6; https://doi.org/info:doi/10.1186/s41182-020-00289-6
• Persistent ID (NDL): info:ndljp/pid/11678918; https://dl.ndl.go.jp/pid/11678918
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2021-06-07T02:06:26+09:00
• Date Created (W3CDTF): 2021-05-19
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Related Material (URI): http://hdl.handle.net/10069/00040612
• Periodical Title (URI): http://hdl.handle.net/10069/00040762
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp