Alternative Title新規バイオアクティブガラス配合覆髄剤の有効性の検討
Note (General)Purpose: We measured the Knoop hardness of demineralized dentin over time using Cariotester to deter- mine the effectiveness of several types of pulp-capping agent for atraumatic indirect pulp capping(AIPC). Methods: Extracted human molars were used to prepare dentin samples with a diameter of 10 mm and thickness of 2 mm. Sound dentin samples were immersed in lactic acid solution and were regarded as demin- eralized when the value obtained using Cariotester was approximately 20 KNH. A new bioactive glass-com- pounded pulp-capping agent(Shofu), Bio MTA cement(J. Morita), and NEX MTA cement(GC)were used as the pulp-capping agents in the present study. Each pulp-capping agent was applied to the surface of demineralized dentin and covered with Base cement. After the Base cement solidified, pulp-capped dentin samples and controls were divided into two groups: those placed in a container with 100% humidity and those immersed in remineralization solution, and stored at 37°C in a thermostatic chamber for l month and 3 months. The hardness of the capping agent-applied region was then measured. Data were analyzed using a one-way analysis of variance and Tukey’s test(α=0.001). Pulp-capping agent-applied surfaces were also observed under SEM. Results: The hardness of demineralized dentin increased with the application of a new bioactive glass-com- pounded pulp-capping agent, Bio MTA cement, and NEX MTA cement, and mineralized substance-like aggregates were deposited on the surface of and between collagen fibers. It is assumed that the demineral- ized dentin had remineralized as the bioactive glass-compounded pulp-capping agent was pasted. Conclusion: These results indicate the effectiveness of the new bioactive glass-compounded pulp-capping agent in the remineralization of demineralized dentin.
2019年度
Collection (particular)国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Date Accepted (W3CDTF)2022-02-06T04:33:19+09:00
Data Provider (Database)国立国会図書館 : 国立国会図書館デジタルコレクション