Effects of Porphyromonas gingivalis on oxidant stress of human bone marrow cells in vitamin E

Persistent ID (NDL): info:ndljp/pid/12071527

Material type: 博士論文

Author: 橋本, 直季

Publisher: -

Publication date: 2019-09-25

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use at the National Diet Library

本資料は、掲載誌(URI)等のリンク先にある学位授与機関のWebサイトやCiNii Dissertationsから、本文を自由に閲覧できる場合があります。

Notes on use

Note (General)：: α-Tocopherol is the most physiologically active member of the vitamin E family, and its role as an antioxidant in various metabolic processes is widel...

Search by Bookstore

Read this material in an accessible format.

View materials in accessible formats for people with print disabilities (1Type)

Search by Bookstore

Read in Disability Resources

Other Services
- テキストデータ check it on 国立国会図書館デジタルコレクション

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Effects of Porphyromonas gingivalis on oxidant stress of human bone marrow cells in vitamin E
Author/Editor: 橋本, 直季
Author Heading: 橋本, 直季
Publication Date: 2019-09-25
Publication Date (W3CDTF): 2019-09-25
Alternative Title: ビタミンE添加状態のPorphyromonas gingivalisがヒト骨髄間葉系細胞の酸化ストレスに及ぼす影響
Degree grantor/type: 大阪歯科大学
Date Granted: 2019-09-25
Date Granted (W3CDTF): 2019-09-25
Dissertation Number: 乙第1622号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 乙第1622号
Text Language Code: eng
Subject Heading: Porphyromonas gingivalis｜VitaminE｜Oxidant stress｜Bone marrow cells
Target Audience: 一般
Note (General): α-Tocopherol is the most physiologically active member of the vitamin E family, and its role as an antioxidant in various metabolic processes is widely recognized. However, vitamin E is often deficient in the human body, and only a few reports are available on the effects of periodontal disease on oxidative stress under vitamin E deficient conditions. We investigated the influence of the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) on oxidative stress in human bone marrow mesenchymal cells (BMMCs) at low concentrations of α-tocopherol. We found an increase in H2O2 production at multiplicity of infection (MOI) of 100 and 1000 at earlier time points and with a concomitant decrease in SOD production. Catalase was produced regardless of P. gingivalis. These results suggest that P. gingivalis reduces the production of some antioxidant enzymes at low concentrations of α-tocopherol and affects the initial cell proliferation and H2O2 production.
2019年度
Persistent ID (NDL): info:ndljp/pid/12071527
https://dl.ndl.go.jp/pid/12071527
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2019-12-11
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000213/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp