Palatal mucosal wound healing in type 2 diabetes model rats after administration of an antibacterial drug

The cover of this title could differ from library to library.

Available in National Diet Library

国立国会図書館デジタルコレクション

Digital data available

Check on the publisher's website

Palatal mucosal wound healing in type 2 diabetes model rats after administration of an antibacterial drug

Persistent ID (NDL): info:ndljp/pid/12071532

Material type: 博士論文

Author: 折原, 博一

Publisher: -

Publication date: 2019-03-27

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use at the National Diet Library

本資料は、掲載誌(URI)等のリンク先にある学位授与機関のWebサイトやCiNii Dissertationsから、本文を自由に閲覧できる場合があります。

Notes on use

Note (General)：: We investigated the effect of antibiotic administration on spontaneous healing in Goto-Kakizaki (GK) rats with type 2 diabetes and an experimentally c...

Search by Bookstore

Read this material in an accessible format.

View materials in accessible formats for people with print disabilities (1Type)

Search by Bookstore

Read in Disability Resources

Other Services
- テキストデータ check it on 国立国会図書館デジタルコレクション

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Palatal mucosal wound healing in type 2 diabetes model rats after administration of an antibacterial drug
Author/Editor: 折原, 博一
Author Heading: 折原, 博一
Publication Date: 2019-03-27
Publication Date (W3CDTF): 2019-03-27
Alternative Title: 抗菌剤を投与した2型糖尿病モデルラット口蓋粘膜の創傷治癒
Degree grantor/type: 大阪歯科大学
Date Granted: 2019-03-27
Date Granted (W3CDTF): 2019-03-27
Dissertation Number: 乙第1618号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 乙第1618号
Text Language Code: eng
Subject Heading: Wound healing｜Diabetes mellitus｜Rats｜Wistar｜Antibacterial drug
Target Audience: 一般
Note (General): We investigated the effect of antibiotic administration on spontaneous healing in Goto-Kakizaki (GK) rats with type 2 diabetes and an experimentally created defect in the palatal mucosa, comparing a control group of 18 male 8-week-old Wistar rats and a diabetes mellitus (DM) group of 18 male 8-week-old GK rats. In both groups, a cylindrical defect 1.5 mm in diameter was created in the maxillary right first molar region of the palatal mucosa using a biopsy punch to remove all the soft tissue, including the periosteum. Immediately after this surgery, an antibiotic was administered intraperitoneally. Three animals per group were sacrificed for histological testing at healing periods of 1, 3, 5, 7, 14 and 28 days after the surgery. It took longer for the wound to be covered with skin in the DM group than in the control group, and the appearance of granulation tissue and collagen fibers in the lamina propria was delayed. No sequestrum for-mation occurred in either group. The results of our comparative histological observations showed that spontaneous healing was delayed in GK rats compared with the controls. Our results suggest that if an antibiotic is administered, sequestrum formation may not occur.
2018年度
Persistent ID (NDL): info:ndljp/pid/12071532
https://dl.ndl.go.jp/pid/12071532
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2019-05-17
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000208/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp