Effect of inverted internal limiting membrane flap technique on small-medium size macular holes

• Material Type: 博士論文
• ISSN: 2045-2322
• Title: Effect of inverted internal limiting membrane flap technique on small-medium size macular holes
• Volume: 12
• Author/Editor: 山田, 香菜子
• Author Heading: 山田, 香菜子
• Publication, Distribution, etc.: Springer Nature
• Publication Date: 2022-03-02
• Publication Date (W3CDTF): 2022-03-02
• Alternative Title: 通常円孔径の黄斑円孔に対する内境界膜翻転法の効果
• Periodical title: Scientific Reports
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2022-03-02
• Date Granted (W3CDTF): 2022-03-02
• Dissertation Number: 甲医歯薬第1403号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医歯薬第1403号
• Text Language Code: eng
• Target Audience: 一般
• Note (General): Inverted internal limiting membrane (ILM) flap technique was developed to achieve macular hole (MH) closure in large MH and refractory cases. In this study, we evaluate the effect of the technique for small-medium size MH. We recruited patients who underwent vitrectomy for small-medium size (< 400 μm) MH with either inverted ILM flap technique (flap group) or with conventional ILM peeling (peeling group). Using propensity score, 21 eyes of 21 patients in the peeling group were matched against 21 eyes of 21 patients in the flap group. We compared MH closure rate, postoperative visual acuity, and recovery of the external limiting membrane (ELM) and ellipsoid zone (EZ). The MH closure rate was not different between the two groups (flap vs peeling: 90% vs 100%, P = 0.49). Whereas there was no significant difference in visual acuity improvement between the two groups, the flap group showed more disruption of the ELM 3 months after surgery and of the EZ at 3 and 6 months after surgery (P = 0.02, P = 0.03, and P = 0.04, respectively). The result suggested that inverted ILM flap technique does not have additional benefits for small-medium size MHs and may delay recovery of retinal integrity.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1403号 学位授与年月日:令和4年3月2日; Author: Kanako Yamada, Akio Oishi, Mao Kusano, Hirofumi Kinoshita, Eiko Tsuiki & Takashi Kitaoka; Citation: Scientific Reports, 12, art.no. 731; 2022; identifier:Nagasaki University (長崎大学), 博士(医学) (2022-03-02); http://hdl.handle.net/10069/00041406
• DOI: info:doi/10.1038/s41598-021-04739-x; https://doi.org/info:doi/10.1038/s41598-021-04739-x
• Persistent ID (NDL): info:ndljp/pid/12297072; https://dl.ndl.go.jp/pid/12297072
• Collection: 障害者向け資料
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• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2022-06-05T18:01:14+09:00
• Date Created (W3CDTF): 2022-05-11
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
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• Related Material (URI): http://hdl.handle.net/10069/00041406
• Periodical Title (URI): http://hdl.handle.net/10069/00041503
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp