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膵癌に対する抗癌薬感受性診断用チップの作成

膵癌に対する抗癌薬感受性診断用チップの作成
Paper図書
佐田尚宏, 自治医科大学 [著][佐田尚宏]2004-2007<Y151-H16591349>
National Diet Library
  • Subject Heading膵癌 / マイクロアレイ / Gemcitabine / 抗癌剤感受性 / 癌遺伝子

プロテインチップを用いたテーラーメード膵癌術後補助化学療法実用化の研究

プロテインチップを用いたテーラーメード膵癌術後補助化学療法実用化の研究
Paper図書
安蒜聡, 外川明, 千葉大学 [著][安蒜聡]2004-2005<Y151-H16591296>
National Diet Library
  • Subject Heading薬剤耐性因子 / 膵癌 / Gemcitabine / Annexin II / テーラーメード / 化学療法

バイオシミュレーションに基づく癌細胞機能の解明と個別化療法への応用

バイオシミュレーションに基づく癌細胞機能の解明と個別化療法への応用
Paper図書
砂村眞琴, 東北大学 [著][砂村眞琴]2006-2007<Y151-H18390358>
National Diet Library
  • Subject Headingメタボローム解析 / 薬剤感受性 / バイオシミュレーション / Gemcitabine / 個別化治療 / 膵癌

超音波内視鏡生検膵癌細胞の遺伝子発現情報解析による膵癌治療の個別的戦略

超音波内視鏡生検膵癌細胞の遺伝子発現情報解析による膵癌治療の個別的戦略
Paper図書
多田稔, 東京大学 [著][多田稔]2002-2004<Y151-H14570447>
National Diet Library
  • Subject Heading膵癌 / 抗癌剤感受性 / Gemcitabine / マイクロアレイ / 薬剤耐性 / 超音波内視鏡

Lauric acid overcomes hypoxia-induced gemcitabine chemoresistance in pancreatic ductal adenocarcinoma

Lauric acid overcomes hypoxia-induced gemcitabine chemoresistance in pancreatic ductal adenocarcinoma
Digital博士論文障害者向け資料あり
Takagi, Tadataka, Fujiwara-Tani, Rina, Mori, Shiori, Kishi, Shingo, Nishiguchi, Yukiko, Sasaki, Takamitsu, Ogata, Ruiko, Ikemoto, Ayaka, Sasaki, Rika, Ohmori, Hitoshi, Luo, Yi, Bhawal, Ujjal Kumar, Sho, Masayuki, Kuniyasu, HirokiMDPI2023-04
National Diet Library
  • Subject Headinggemcitabine drug resistance hypoxia mitoc...
  • Note (General)type:Thesis Although gemcitabine (GEM) is widely used in chemo...

Gemcitabine plus nab-paclitaxel as second-line chemotherapy following FOLFIRINOX in patients with unresectable pancreatic cancer : A single-institution, retrospective analysis

Gemcitabine plus nab-paclitaxel as second-line chemotherapy following FOLFIRINOX in patients with unresectable pancreatic cancer : A single-institution, retrospective analysis
Digital博士論文
野村, 琴音2024-03-24
National Diet Library
  • Subject HeadingPancreatic cancer Gemcitabine Nab-paclitaxel FOLFIRINOX Sec...

The effect of gemcitabine on cell cycle arrest and microRNA signatures in pancreatic cancer cells

The effect of gemcitabine on cell cycle arrest and microRNA signatures in pancreatic cancer cells
Digital博士論文障害者向け資料あり
波間, 大輔2020-12-24
National Diet Library
  • Subject HeadingPancreatic neoplasm cell cycle cyclin gemcitabine microRNA
  • Note (General)Background/aim: Gemcitabine, an inhibitor ...... the effect of gemcitabine on PDAC cells ...... the effect of gemcitabine on the cell cy......ds: Effects of gemcitabine on PK-1 and PK......used to assess gemcitabine effects in vivo. Results: Gemcitabine inhibited the ......e altered upon gemcitabine treatment of P......he efficacy of gemcitabine in PDAC.

microRNA-99a-5pはSMARCD1を標的としてゲムシタビン抵抗性膀胱癌の細胞老化を誘導する

microRNA-99a-5pはSMARCD1を標的としてゲムシタビン抵抗性膀胱癌の細胞老化を誘導する
Digital博士論文障害者向け資料あり
玉井, 元規Federation of European Biochemical Societies / John Wiley & Sons Ltd2022-10-18
National Diet Library
  • Subject Headingbladder cancer cellular senescence gemcitabine resistance miR-99a-5p SMARCD1
  • Note (General)...ics, including gemcitabine, but the effec......e mechanism of gemcitabine resistance. First, gemcitabine-resistant cell......As involved in gemcitabine resistance. mi......sensitivity to gemcitabine. RNA sequencin......restoration of gemcitabine sensitivity. m......lso suppressed gemcitabine-resistant cell...... senescence in gemcitabine-resistant blad...... senescence in gemcitabine-resistant bladder cancer by t...
  • Alternative Title... senescence in gemcitabine-resistant bladder cancer by t...

Efficacy and safety of S-1 following gemcitabine with cisplatin for advanced biliary tract cancer 39

Efficacy and safety of S-1 following gemcitabine with cisplatin for advanced biliary tract cancer 39
Digital博士論文障害者向け資料あり
井上, 博登, INOUE, HirotoSpringer Nature2021-10Investigational New Drugs
National Diet Library
  • Subject HeadingBiliary tract cancer S-1 Gemcitabine and cisplatin Second-line the...
  • Note (General)...ion therapy of gemcitabine with cisplatin......fety following gemcitabine monotherapy. However, few stu...

A phase I/II study of fixed-dose-rate gemcitabine and S-1 with concurrent radiotherapy for locally advanced pancreatic cancer 76 3

A phase I/II study of fixed-dose-rate gemcitabine and S-1 with concurrent radiotherapy for locally advanced pancreatic cancer 76 3
Digital博士論文障害者向け資料あり
Goji, Takahiro, Kimura, Tetsuo, Miyamoto, Hiroshi, Takehara, Masanori, Kagemoto, Kaizo, Okada, Yasuyuki, Okazaki, Jun, Takaoka, Yoshifumi, Miyamoto, Yoshihiko, Mitsui, Yasuhiro, Matsumoto, Sayo, Sueuchi, Tatsuhisa, Tanaka, Kumiko, Fujino, Yasuteru, Takaoka, Toshi, Kitamura, Shinji, Okamoto, Koichi, Kimura, Masako, Sogabe, Masahiro, Muguruma, Naoki, Okahisa, Toshiya, Sato, Yasuhiro, Sagawa, Tamotsu, Fujikawa, Koji, Sato, Yasushi, Ikushima, Hitoshi, Takayama, TetsujiSpringer nature2015-07-29Cancer Chemotherapy and Pharmacology
National Diet Library
  • Subject HeadingPancreatic cancer Chemoradiotherapy Fixed-dose-rate gemcitabine S-1 gemcitabine radiosensitizer
  • Note (General)...ixed-dose-rate gemcitabine (FDR-gem) admi......re 300mg/m2 of gemcitabine and 60mg/m2 of S-1 daily. The...

A phase II study of gemcitabine plus nab-paclitaxel as first-line therapy for locally advanced pancreatic cancer

A phase II study of gemcitabine plus nab-paclitaxel as first-line therapy for locally advanced pancreatic cancer
Digital博士論文障害者向け資料あり
深堀, 理2021-10-01
National Diet Library
  • Subject Headingclinical trial converting to surgical resection first-line chemotherapy gemcitabine nab-paclitaxel

Predictive factors of the treatment outcome in patients with advanced biliary tract cancer receiving gemcitabine plus cisplatin as first-line chemotherapy 54 3

Predictive factors of the treatment outcome in patients with advanced biliary tract cancer receiving gemcitabine plus cisplatin as first-line chemotherapy 54 3
Digital博士論文障害者向け資料あり
鈴木, 裕子2019-03Journal of gastroenterology
National Diet Library
  • Subject HeadingBiliary tract cancer Chemotherapy Gemcitabine and cisplatin Prognostic fact...
  • Note (General)...BTC) receiving gemcitabine plus cisplatin (GC) which is ...

Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells. 21 20

Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells. 21 20
Digital博士論文障害者向け資料あり
Kitagawa, Koh, Moriya, Kei, Kaji, Kosuke, Saikawa, Soichiro, Sato, Shinya, Nishimura, Norihisa, Namisaki, Tadashi, Akahane, Takemi, Mitoro, Akira, Yoshiji, HitoshiMDPI2020-10-14International journal of molecular sciences
National Diet Library
  • Subject Heading...-CoA reductase gemcitabine TEAD transcriptional activati...
  • Note (General)...o conventional gemcitabine-based chemothe......mbination with gemcitabine on the progres......orvastatin and gemcitabine concentration-......orvastatin and gemcitabine potently repre...... indicate that gemcitabine plus atorvastatin could serve...

Overexpression of karyopherin- 2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins.

Overexpression of karyopherin- 2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins.
Digital博士論文障害者向け資料あり
塚越, 真梨子群馬大学医学系研究科2017-03-23
National Diet Library
  • Subject HeadingKPNA2 cholangiocarcinoma gemcitabine MRN complex DNA repair

Investigation into metastatic processes and the therapeutic effects of gemcitabine on human pancreatic cancer using an orthotopic SUIT-2 pancreatic cancer mouse model.

Investigation into metastatic processes and the therapeutic effects of gemcitabine on human pancreatic cancer using an orthotopic SUIT-2 pancreatic cancer mouse model.
Digital博士論文障害者向け資料あり
樋口, 珠美群馬大学医学系研究科2019-03-22
National Diet Library
  • Subject Heading...s chemotherapy gemcitabine

Mechanism of gemcitabine-induced suppression of human cholangiocellular carcinoma cell growth

Mechanism of gemcitabine-induced suppression of human cholangiocellular carcinoma cell growth
Digital博士論文
豊田, 由花2015-09-29
National Diet Library
  • Subject Headinggemcitabine cholangiocellular carcinoma m...
  • Note (General)AbstractAlthough gemcitabine (2',2'-difluor......ry effects and gemcitabine resistance in ......umor effect of gemcitabine and to analyze......vitro CCC cell gemcitabine resistance. In......mor effects of gemcitabine in CCCs. Using......the ability of gemcitabine to inhibit cel......the effects of gemcitabine on cell cycle-......hips to assess gemcitabine-mediated chang......sively analyze gemcitabine-induced miRNAs......th and without gemcitabine treatment. Gemcitabine inhibited cell......nd TKKK cells. Gemcitabine inhibited cell....... In addition, gemcitabine upregulated th......, by contrast, gemcitabine did not arrest the cell cycle...

Potent effect of adenoviral vector expressing short hairpin RNA targeting ribonucleotide reductase large subunit M1 on cell viability and chemotherapeutic sensitivity to gemcitabine in non-small cell lung cancer cells

Potent effect of adenoviral vector expressing short hairpin RNA targeting ribonucleotide reductase large subunit M1 on cell viability and chemotherapeutic sensitivity to gemcitabine in non-small cell lung cancer cells
Digital博士論文
徳永, 義昌2016-03-24
National Diet Library
  • Subject HeadingRRM1 shRNA Adenovirus Gene therapy Gemcitabine Chemotherapeutic sensitivity
  • Note (General)...lar target for gemcitabine (GEM). Overexp......sensitivity to gemcitabine of each type of RRM1-overexpr...

Human equilibrative nucleoside transporter-1 (hENT1) expression in endoscopic ultrasonography-guided fine-needle aspiration biopsy samples is a strong predictor of clinical response and survival in the patients with pancreatic ductal adenocarcinoma undergoing gemcitabine-based chemoradiotherapy

Human equilibrative nucleoside transporter-1 (hENT1) expression in endoscopic ultrasonography-guided fine-needle aspiration biopsy samples is a strong predictor of clinical response and survival in the patients with pancreatic ductal adenocarcinoma undergoing gemcitabine-based chemoradiotherapy
Digital博士論文障害者向け資料あり
Yamada, Reiko三重大学2016-03-25
National Diet Library
  • Subject HeadingEUS-FNAB hENT1 chemoradiotherapy gemcitabine pancreatic ductal adenocarcin...
  • Note (General)...specimen after gemcitabine-based chemoradiotherapy (Gem-...

肝内胆管癌におけるRibonucleotide Reductase M1発現の臨床学的意義 : Gemcitabine治療抵抗性

肝内胆管癌におけるRibonucleotide Reductase M1発現の臨床学的意義 : Gemcitabine治療抵抗性
Digital博士論文障害者向け資料あり
堅田, 朋大新潟大学2017-09-20
National Diet Library
  • Subject Heading肝内胆管癌 Gemcitabine RRM1 術前化学療法 外科切除
  • Note (General)【目的】Gemcitabine（以下GEM）の代謝経路において，リボヌクレオチド還元酵素の...
  • Alternative Title... M1発現の臨床学的意義 : Gemcitabine治療抵抗性 Clinical ......sociation with Gemcitabine Resistance

Lauric acid overcomes hypoxia-induced gemcitabine chemoresistance in pancreatic ductal adenocarcinoma

Lauric acid overcomes hypoxia-induced gemcitabine chemoresistance in pancreatic ductal adenocarcinoma
Digital博士論文
Takagi, Tadataka, Fujiwara-Tani, Rina, Mori, Shiori, Kishi, Shingo, Nishiguchi, Yukiko, Sasaki, Takamitsu, Ogata, Ruiko, Ikemoto, Ayaka, Sasaki, Rika, Ohmori, Hitoshi, Luo, Yi, Bhawal, Ujjal Kumar, Sho, Masayuki, Kuniyasu, HirokiMDPI2023-04International Journal of Molecular Sciences24 8p.7506-
Available onlineOther Libraries in Japan
  • Subject Headinggemcitabine drug resistance hypoxia mitoc...
  • Note (General)type:Thesis Although gemcitabine (GEM) is widely used in chemo...
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