Search results 5
Digital博士論文障害者向け資料あり
National Diet Library
- Subject HeadingmicroRNA miR-30a-5p RRM2 pancreatic ductal adenocarci...
- Note (General)... regulation of RRM2 by miR-30a-5p......rexpression of RRM2 was demonstra......4 genes (CBFB, RRM2, AHNAK, and D......t knockdown of RRM2 attenuated th......The miR-30a-5p/RRM2 axis facilitated the maligna...
Digital博士論文
National Diet Library
- Subject HeadingRRM1 shRNA Adenovirus Gene therap...
- Note (General)...large subunit (RRM1) is the main ......rexpression of RRM1 is reportedly......herapy against RRM1-overexpressin...... targeting the RRM1 gene (Ad-shRRM1) was constructed. Two RRM1-overexpressin...... Results: Ad-shRRM1 effectively downregulated RRM1 mRNA and prot......ection with Ad-RRM1 increased the......either type of RRM1-overexpressin......ment with Ad-shRRM1 exerted a pot......ct against the RRM1-overexpressin......thermore, Ad-shRRM1-mediated inhibition of RRM1 specifically ......f each type of RRM1-overexpressin......ment with Ad-shRRM1 and GEM exert......tion than Ad-shRRM1 or GEM treatm......e. Conclusion: RRM1 appeared to be a promising t...
Digital博士論文障害者向け資料あり
National Diet Library
- Subject Heading肝内胆管癌 Gemcitabine RRM1 術前化学療法 外科切除
- Note (General)...Reductase M1(以下RRM1)はGEMの作用機序に重要な......究の目的は,肝内胆管癌におけるRRM1発現を免疫組織化学にて検討し......EM基盤の術前化学療法の効果とRRM1発現との関連を明らかにするこ......ガイドラインに準じて判定した.RRM1発現は免疫組織化学により評価......または陰性に分類した.【結果】RRM1発現陽性は43例中27例(6......化学療法を施行した4例中3例はRRM1発現陽性であり,腫瘍縮小率は......SD)と判定された.残り1例はRRM1発現陰性で,腫瘍縮小率は68......EM基盤の術前化学療法の効果はRRM1発現と関連していることが示唆される.高度局所進展を伴う肝内...
Digital博士論文
Available onlineOther Libraries in Japan
- Subject HeadingRRM1 shRNA Adenovirus Gene therap...
Digital博士論文
Available onlineOther Libraries in Japan
- Subject HeadingmicroRNA miR-30a-5p RRM2 pancreatic ductal adenocarci...
- Note (General)... regulation of RRM2 by miR-30a-5p......rexpression of RRM2 was demonstra......4 genes (CBFB, RRM2, AHNAK, and D......t knockdown of RRM2 attenuated th......The miR-30a-5p/RRM2 axis facilitated the maligna...
Reached to the end of result.